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TranscriptomicsDrosophila Ecdysone Receptor Study
We used the DamID method to systematically identify the binding sites of Ecdysone Receptor and its heterodimeric partner USP across the whole genome in Drosophila Kc cells. We find that the EcR sites are a subset of the USP sites and that only a proportion are ecdysone regulated from an accompanying...
ORGANISM(S): Drosophila melanogaster 
2008-05-01 | E-GEOD-9156 | biostudies-arrayexpress
TranscriptomicsEcdysone Response Timecourse in Kc Cells
Kc167 Cells were plated at 0.5x106/ml and grown at 23.50C. They were treated with 20-HE (Sigma) at a final concentration of 5x10-7M. The reference sample was total RNA isolated at 0 hr. after treatment. The experimental samples were total RNA isolated from cells treated for 1, 3, 6, 12, 24, and 48 h...
ORGANISM(S): Drosophila melanogaster 
2008-06-12 | E-GEOD-11625 | biostudies-arrayexpress
TranscriptomicsA direct role for cohesin in genome-wide gene regulation and Ecdysone-response in Drosophila salivary gland
Developmental abnormalities observed in Cornelia de Lange Syndrome (CdLS) have been genetically linked to mutations in the cohesin machinery. These findings raise the possibility that cohesin, in addition to its canonical function of mediating sister chromatid cohesion, might also be involved in reg...
ORGANISM(S): Drosophila melanogaster 
2011-03-22 | E-GEOD-21874 | biostudies-arrayexpress
TranscriptomicsTime course of response of ML-DmBG3-c2 cells to ecdysone
The changes in transcript titers are described for Drosophila ML-DmBG3-c2 cells following 5-48 hr treatment with 20-hydroxyecdysone. Keywords: hormone response RNA from ecdysone-treated cells was compared to RNA from cells treated with carrier alone. A total of 4 slides were analyzed for each time p...
ORGANISM(S): Drosophila melanogaster 
2009-03-19 | E-GEOD-11069 | biostudies-arrayexpress
GenomicsDistribution of Drosophila insulator proteins after ecdysone treatment in Kc cells
Here we examine changes in the distribution of Drosophila insulator proteins during the ecdysone response. We performed ChIP-seq analysis in Kc cells at 0, 3, and 48 hours of ecdysone treatment with antibodies against CP190, Su(Hw), dCTCF, and BEAF-32B. Examination of 4 different insulator proteins...
ORGANISM(S): Drosophila melanogaster 
2011-10-13 | E-GEOD-30740 | biostudies-arrayexpress
TranscriptomicsKc cells from Drosophila melanogaster during ecdysone treatment and CP190 knockdown
This SuperSeries is composed of the following subset Series: GSE30686: Gene expression analysis of Kc cells from Drosophila melanogaster during ecdysone treatment and CP190 knockdown GSE30740: Distribution of Drosophila insulator proteins after ecdysone treatment in Kc cells Refer to individual Seri...
ORGANISM(S): Drosophila melanogaster 
2011-10-13 | E-GEOD-30741 | biostudies-arrayexpress
TranscriptomicsEcR mutant midgut comparison
Comparisons between EcR mutant midgut and a reference control sample from mixed-stage normal midgut Keywords = Drosophila, ecdysone, network, genomic, microarray, organogenesis, EcR, midgut, central nervous system, salivary gland, epidermis, imaginal disc, development
ORGANISM(S): Drosophila melanogaster 
2010-06-05 | E-GEOD-540 | biostudies-arrayexpress
TranscriptomicsDifferential gene expression profiling in the presence and absence of cohesin in Drosophila salivary glands (gene expression data)
Analysis of differential gene expression in third instar Drosophila salivary glands in the absence versus presence of cohesin. ABSTRACT: Developmental abnormalities observed in Cornelia de Lange Syndrome (CdLS) have been genetically linked to mutations in the cohesin machinery. These findings raise ...
ORGANISM(S): Drosophila melanogaster 
2010-12-22 | E-GEOD-21844 | biostudies-arrayexpress
Transcriptomicssage gene RNAi experiment
Comparisons between the salivary glands upon the RNAi of sage gene vs. the control. Keywords = Drosophila, ecdysone, network, genomic, microarray, organogenesis, EcR, midgut, central nervous system, salivary gland, epidermis, imaginal disc, development
ORGANISM(S): Drosophila melanogaster 
2010-06-05 | E-GEOD-283 | biostudies-arrayexpress
GenomicsThe ecdysone receptor promotes or suppresses proliferation according to ligand level
The ecdysone receptor promotes or suppresses proliferation according to ligand level
PRJNA989161 | ENA
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