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GenomicsRNA sequencing in ovarian cancer cell line HEYA8 in terms of ECM1 silencing and reintroduction of ECM1 subtypes ECM1a and ECM1b
RNA sequencing in ovarian cancer cell line HEYA8 in terms of ECM1 silencing and reintroduction of ECM1 subtypes ECM1a and ECM1b
PRJNA719542 | ENA
ProteomicsHuman, ovarian epithelial cancer cell line, LC-MSMS
We investigated the functions of ECM1 subtypes ECM1a (inlcuding wild type and mutant) and ECM1b in ovarian cancer cell line HEYA8. While ECM1a is oncogenic, ECM1b is a tumor suppressor. To identify the molecules binding to ECM1a or ECM1b within cells, protein samples were generated by co-IP using HA...
ORGANISM(S): Homo sapiens (Human) 
2021-05-27 | PXD025239 | Pride
Human Ecm1 subtypes Ecm1a wild type (wt) Ecm1b Ecm1a mutant (mt) Ovarian epithelial cell line 
TranscriptomicsRNA sequencing in ovarian cancer cell line HEYA8 in terms of ECM1 silencing and reintroduction of ECM1 subtypes ECM1a and ECM1b
Extracellular Matrix Protein-1 (ECM1) promotes tumorigenesis in multiple organs, but the mechanisms associated with the functions and putative receptors of ECM1 subtypes have yet to be systematically clarified. We found in this study that secretory ECM1a functions as an oncoprotein to induce tumorig...
ORGANISM(S): Homo sapiens 
2021-05-27 | GSE171425 | GEO
UnknownExtracellular matrix protein-1 secretory isoform promotes ovarian cancer through increasing alternative mRNA splicing and stemness.
Not available
S-EPMC8270969 | biostudies-literature
UnknownTAGET: a toolkit for analyzing full-length transcripts from long-read sequencing.
Not available
S-EPMC10518008 | biostudies-literature
UnknownClinical and molecular study of the extracellular matrix protein 1 gene in a spanish family with lipoid proteinosis.
Not available
S-EPMC3896652 | biostudies-literature
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