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ProteomicsAn insight into the proteome of uveal melanoma-derived ectosomes reveals the presence of potentially useful biomarkers
Cancer cells are known to release extracellular vesicles that often promote disease development and progression. The present study investigated protein content and glycosylation pattern of ectosomes released in vitro by human primary uveal melanoma Mel202 cell line. Ectosomes released by Mel202 cell...
ORGANISM(S): Homo sapiens (Human) 
2019-08-08 | PXD012003 | Pride
Glycosylation Uveal melanoma Proteomics Extracellular vesicles Lectins Ectosomes 
ProteomicsComparative proteomic profiling of ectosomes derived from thyroid carcinoma and normal thyroid cells uncovers multiple proteins with functional implications in cancer
Proteins carried by tumor-derived ectosomes play an important role in cancer progression and are considered promising diagnostic markers. In the present study a shotgun nanoLC-MS/MS proteomic approach was applied to profile and compare the protein content of ectosomes released in vitro by normal hum...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-02-17 | MSV000088850 | MassIVE
ProteomicsMass spectrometry-based proteomic characterization of cutaneous melanoma ectosomes reveals the presence of cancer-related molecules
Cutaneous melanoma (CM) is an aggressive type of skin cancer for which effective biomarkers are still needed. Due to the development of protocols for their successful isolation, protein content of extracellular vesicles (EVs) (including ectosomes and exosomes) became increasingly investigated in ter...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-02-03 | MSV000084892 | MassIVE
TranscriptomicsEffects of PMN-Ectosomes on human macrophages
In order to define the inhibitory activity of PMN-Ectosomes, we investigated the early gene expression profiles of resting and zymosan A-stimulated human monocyte-derived macrophages in the absence or presence of PMN-Ectosomes.
ORGANISM(S): Homo sapiens 
2009-01-16 | GSE14419 | GEO
GenomicsTranscriptome profiling data of THP-1 cells upon Huh7 cell-derived ectosomes incubation
Transcriptome profiling data of THP-1 cells upon Huh7 cell-derived ectosomes incubation
PRJNA548077 | ENA
ProteomicsProteomic profiling of ectosomes derived from paired urothelial bladder cancer and normal cells reveals the presence of biologically-relevant molecules
Protein content of extracellular vesicles (EVs) can modulate different processes during carcinogenesis. Novel proteomic strategies have been applied several times to profile proteins present in exosomes released by urothelial bladder cancer (UBC) cells. However, similar studies have not been conduct...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-05-06 | MSV000087370 | MassIVE
UnknownComparative Analysis of Ciliary Membranes and Ectosomes.
Not available
S-EPMC5173405 | biostudies-literature
UnknownThe cilium secretes bioactive ectosomes.
Not available
S-EPMC3850760 | biostudies-literature
UnknownProteogenomic analysis reveals exosomes are more oncogenic than ectosomes.
Not available
S-EPMC4558158 | biostudies-literature
TranscriptomicsTranscriptome profiling data of THP-1 cells upon Huh7 cell-derived ectosomes incubation
Analysis of the transcriptome of THP-1 cells upon Huh7 cell-derived ectosomes incubation. Monocytic THP-1 cells were incubated with or without ectosomes (10 mg/ml) derived from scramble sequence transfection (Scramble Ecto) or PKM2 knocking down (PKM2 KD Ecto) Huh7 cells for 24 h. Results provide a ...
ORGANISM(S): Homo sapiens 
2022-06-08 | GSE132435 | GEO
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