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TranscriptomicsDkk4 and Eda regulate distinctive developmental mechanisms for subtypes of mouse hair
This SuperSeries is composed of the following subset Series: GSE19309: Dkk4 and Eda regulate distinctive developmental mechanisms for subtypes of mouse hair-1 GSE19312: Dkk4 and Eda regulate distinctive developmental mechanisms for subtypes of mouse hair-2 Refer to individual Series
ORGANISM(S): Mus musculus 
2010-09-03 | E-GEOD-19364 | biostudies-arrayexpress
TranscriptomicsDkk4 and Eda regulate distinctive developmental mechanisms for subtypes of mouse hair-2
Dkk4 transgenic mice in Tabby background lack hair follicle formation. Gene expression profiling showed significant down regulation of Shh pathway genes at E16.5 and E17.5, the secondary hair follicle induction stages. Keywords: development or differentiation design,genetic modification design To d...
ORGANISM(S): Mus musculus 
2010-09-03 | E-GEOD-19312 | biostudies-arrayexpress
TranscriptomicsDkk4 and Eda regulate distinctive developmental mechanisms for subtypes of mouse hair-1
Dkk4 transgenic mice in wild-type background showed abnormal hair subtype formation. Gene expression profiling showed significant down regulation of hair follicle-related keratin genes and hair keratin-associated protein genes at E18.5 and P1. Keywords: development or differentiation design,genetic...
ORGANISM(S): Mus musculus 
2010-09-03 | E-GEOD-19309 | biostudies-arrayexpress
TranscriptomicsEctodysplasin regulates the lymphotoxin-beta pathway for hair differentiation
To find developmental stage specific genes controled by EDA Keywords: development or differentiation design,genetic modification design Triplicated for all samples
ORGANISM(S): Mus musculus 
2010-06-12 | E-GEOD-6952 | biostudies-arrayexpress
GenomicsTranscriptomic changes in F9 tumors after EDA-CART cell therapy
Transcriptomic changes in F9 tumors after EDA-CART cell therapy
PRJNA842673 | ENA
TranscriptomicsCascade regulation of sweat gland development by Wnt, Eda and Shh pathways [Dkk4 transgenic]
Millions of sweat glands required to maintain body temperature develop from embryonic ectoderm by a poorly defined mechanism. We present evidence for temporal cascade regulation of sweat gland development by Wnt, Eda and Shh pathways. The first stage, sweat gland induction, failed completely when Wn...
ORGANISM(S): Mus musculus 
2014-08-20 | E-GEOD-50862 | biostudies-arrayexpress
TranscriptomicsRequirement for Shh and Fox family genes at different stages in sweat gland development (E16.5)
Sweat glands play a fundamental role in thermal regulation in man, but the molecular mechanism of their development remains unknown. To initiate analyses, we compared the model of Eda mutant Tabby mice, in which sweat glands were not formed, to wild-type mice. We inferred developmental stages and c...
ORGANISM(S): Mus musculus 
2010-05-05 | E-GEOD-14871 | biostudies-arrayexpress
TranscriptomicsRequirement for Shh and Fox family genes at different stages in sweat gland development (E15.5)
Sweat glands play a fundamental role in thermal regulation in man, but the molecular mechanism of their development remains unknown. To initiate analyses, we compared the model of Eda mutant Tabby mice, in which sweat glands were not formed, to wild-type mice. We inferred developmental stages and c...
ORGANISM(S): Mus musculus 
2010-05-05 | E-GEOD-14870 | biostudies-arrayexpress
TranscriptomicsRequirement for Shh and Fox family genes at different stages in sweat gland development (Adult)
Sweat glands play a fundamental role in thermal regulation in man, but the molecular mechanism of their development remains unknown. To initiate analyses, we compared the model of Eda mutant Tabby mice, in which sweat glands were not formed, to wild-type mice. We inferred developmental stages and c...
ORGANISM(S): Mus musculus 
2010-05-05 | E-GEOD-14877 | biostudies-arrayexpress
TranscriptomicsRequirement for Shh and Fox family genes at different stages in sweat gland development (P5)
Sweat glands play a fundamental role in thermal regulation in man, but the molecular mechanism of their development remains unknown. To initiate analyses, we compared the model of Eda mutant Tabby mice, in which sweat glands were not formed, to wild-type mice. We inferred developmental stages and c...
ORGANISM(S): Mus musculus 
2010-05-05 | E-GEOD-14876 | biostudies-arrayexpress
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