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GenomicsThe enhancer and promoter landscape of human regulatory and conventional T cell subpopulations
CD4+CD25+FOXP3+ human regulatory T cells (Treg) are essential for self-tolerance and immune homeostasis. Here, we generated genome-wide maps of poised and active enhancer elements marked by histone H3 lysine 4 monomethylation and histone H3 lysine 27 acetylation for CD4+CD25highCD45RA+ naive and CD4...
ORGANISM(S): Homo sapiens 
2014-04-01 | E-GEOD-43119 | biostudies-arrayexpress
TranscriptomicsInfluence of isolation procedure and storage condition on the ex vivo gene expression pattern in peripheral human effector/memory T helper lymphocytes
Gene expression profiling of cells isolated ex vivo is a unique tool to assess gene expression in vivo. Exemplified for CD4+CD45RO+ effector/memory T helper (T E/M) lymphocytes of human peripheral blood, we have analyzed different isolation procedures and storage conditions for the introduction of b...
ORGANISM(S): Homo sapiens 
2014-03-24 | E-GEOD-54247 | biostudies-arrayexpress
UnknownAge-Dependent FOSB/ΔFOSB Response to Acute and Chronic Stress in the Extended Amygdala, Hypothalamic Paraventricular, Habenular, Centrally-Projecting Edinger-Westphal, and Dorsal Raphe Nuclei in Male Rats.
Not available
S-EPMC9110804 | biostudies-literature
TranscriptomicsGene expression of resting memory, resting naive and in vitro activated memory CD8+CD127+ T cells from spleen and bone marrow (BM)
To understand differences between resting and activated memory CD8+ T cells, we compared the global gene expression of ex vivo isolated naive and spleen and BM memory cells to in vitro activated spleen and BM memory cells. Single cell suspension from the spleen and bones of aged C57BL/6 mice were pr...
ORGANISM(S): Mus musculus 
2015-02-05 | E-GEOD-62691 | biostudies-arrayexpress
TranscriptomicsGene expression in primary human B cells sorted according to IL-10 secretion or not after 2 days of activation.
To determine characterize human B cells that express IL-10 on a molecular level, we compared the global gene expression of primary CD19pos B cells secreting IL-10 or not, upon activation with anti-CD40, IL-4 and CpG for 2 days. Human B cells from healthy donors were sorted according to CD19 expressi...
ORGANISM(S): Homo sapiens 
2014-03-24 | E-GEOD-49853 | biostudies-arrayexpress
UnknownNeurodegeneration in the centrally-projecting Edinger-Westphal nucleus contributes to the non-motor symptoms of Parkinson's disease in the rat.
Not available
S-EPMC8809039 | biostudies-literature
UnknownAstrocytic Calcium Waves Signal Brain Injury to Neural Stem and Progenitor Cells.
Not available
S-EPMC5355570 | biostudies-literature
UnknownArginine Methylation Regulates MEIS2 Nuclear Localization to Promote Neuronal Differentiation of Adult SVZ Progenitors.
Not available
S-EPMC5998649 | biostudies-literature
UnknownVesicular glutamate transporter 2-containing neurons of the centrally-projecting Edinger-Westphal nucleus regulate alcohol drinking and body temperature.
Not available
S-EPMC8694014 | biostudies-literature
UnknownNeuromedin U Neurons in the Edinger-Westphal Nucleus Respond to Alcohol Without Interfering with the Urocortin 1 Response.
Not available
S-EPMC11502588 | biostudies-literature
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