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TranscriptomicsGene Copy Number Aberrations are Associated with Survival in Histological Subgroups of Non-Small Cell Lung Cancer (copy number data)
Hypothesis: Non-small cell lung cancer (NSCLC) is characterized by a multitude of genetic aberrations with unknown clinical impact. In this study, we aimed to identify gene copy number changes that correlate with clinical outcome in NSCLC. To maximize the chance to identify clinically relevant event...
ORGANISM(S): Homo sapiens 
2011-11-01 | E-GEOD-28572 | biostudies-arrayexpress
TranscriptomicsGene Copy Number Aberrations are Associated with Survival in Histological Subgroups of Non-Small Cell Lung Cancer (expression data)
Hypothesis: Non-small cell lung cancer (NSCLC) is characterized by a multitude of genetic aberrations with unknown clinical impact. In this study, we aimed to identify gene copy number changes that correlate with clinical outcome in NSCLC. To maximize the chance to identify clinically relevant event...
ORGANISM(S): Homo sapiens 
2011-10-27 | E-GEOD-28571 | biostudies-arrayexpress
TranscriptomicsCD99 is a novel prognostic stromal marker in non-small cell lung cancer
The delicate interaction between cancer cells and the surrounding stroma plays an essential role in all stages of tumourigenesis. Despite the significance of this interplay, alterations in protein composition underlying tumour-stroma interactions are largely unknown. The aim of this study was to ide...
ORGANISM(S): Homo sapiens 
2012-06-05 | E-GEOD-33363 | biostudies-arrayexpress
MetabolomicsMetabolic profiling of ob/ob mouse fatty liver using HR-MAS 1H-NMR combined with gene expression analysis reveals alterations in betaine metabolism and the transsulfuration pathway
Metabolic perturbations resulting from excessive hepatic fat accumulation are poorly understood. Thus, in this study, leptin-deficient ob/ob mice, a mouse model of fatty liver disease, were used to investigate metabolic alterations in more detail. Metabolites were quantified in intact liver tissues ...
2018-01-31 | MTBLS400 | MetaboLights
TranscriptomicsBiomarker discovery in non-small cell lung cancer: integrating gene expression profiling, meta-analysis and tissue microarray validation
Background: Global gene expression profiling has been widely used in lung cancer research to identify clinically relevant molecular subtypes as well as to predict prognosis and therapy response. So far, the value of these multi-gene signatures in clinical practice is unclear and the biological impor...
ORGANISM(S): Homo sapiens 
2012-10-12 | E-GEOD-37745 | biostudies-arrayexpress
TranscriptomicsNext Generation Sequencing (RNAseq) of non-small cell lung cancer
Cancer testis antigens (CTAs) are of clinical interest as biomarkers and present valuable targets for immunotherapy. To comprehensively characterize the CTA landscape of non-small cell lung cancer (NSCLC), we compared RNAseq data of 199 NSCLC tissues to the normal transcriptome of 142 samples from 3...
ORGANISM(S): Homo sapiens 
2016-06-01 | E-GEOD-81089 | biostudies-arrayexpress
ModelsUhlén2015 - Human tissue-based proteome metabolic network - lymph node
Uhlén2015 - Human tissue-based proteome metabolic network - lymph node Human lymph node specific proteome metabolic network This model is described in the article: Tissue-based map of the human proteome Uhlén M, Fagerberg L, Hallström BM, Lindskog C, Oksvold P, Mardinogl...
2015-01-28 | MODEL1411240016 | BioModels
ModelsUhlén2015 - Human tissue-based proteome metabolic network - prostate
Uhlén2015 - Human tissue-based proteome metabolic network - prostate Human prostate specific proteome metabolic network This model is described in the article: Tissue-based map of the human proteome Uhlén M, Fagerberg L, Hallström BM, Lindskog C, Oksvold P, Mardinoglu A,...
2015-01-28 | MODEL1411240028 | BioModels
ModelsUhlén2015 - Human tissue-based proteome metabolic network - skin
Uhlén2015 - Human tissue-based proteome metabolic network - skin Human skin specific proteome metabolic network This model is described in the article: Tissue-based map of the human proteome Uhlén M, Fagerberg L, Hallström BM, Lindskog C, Oksvold P, Mardinoglu A, Siverts...
2015-01-28 | MODEL1411240022 | BioModels
ModelsUhlén2015 - Human tissue-based proteome metabolic network - kidney
Uhlén2015 - Human tissue-based proteome metabolic network - kidney Human kidney specific proteome metabolic network This model is described in the article: Tissue-based map of the human proteome Uhlén M, Fagerberg L, Hallström BM, Lindskog C, Oksvold P, Mardinoglu A, Siv...
2015-01-28 | MODEL1411240019 | BioModels
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