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TranscriptomicsDiurnal gene expression in Populus wild type and lhy RNAi line 10
Previous studies have shown that a considerable proportion of the Arabidopsis genome cycles under circadian and/or diurnal conditions (Edwards et al., 2006 PMID: 16473970, Blaesing et al., 2005 PMID 16299223). It is likely that the correct phasing of gene expression plays an important role in improv...
ORGANISM(S): Populus tremula x Populus tremuloides 
2018-03-13 | E-MTAB-4516 | biostudies-arrayexpress
GenomicsICGC Oesophageal Adenocarcinoma sequence data - mobile_elements - samples
Samples from Edwards et al 2015 - doi:10.1186/s12864-015-1685-z
EGAD00001001048 | EGA
MetabolomicsMetabolic profiling of rheumatoid arthritis neutrophils reveals altered energy metabolism that is not affected by JAK inhibition
Neutrophils play a key role in the pathophysiology of rheumatoid arthritis (RA) where release of ROS and proteases directly causes damage to joints and tissues. Neutrophil function is directly affected by Janus Kinase (JAK) inhibitor drugs, including tofacitinib and baricitinib, which are clinically...
2023-07-11 | MTBLS4766 | MetaboLights
ProteomicsA Cell-based Systems Biology Assessment of Human Blood to Monitor Immune Responses After Influenza Vaccination
Systems biology is an approach to comprehensively study complex interactions within a biological system. Most published systems vaccinology studies have utilized whole blood or peripheral blood mononuclear cells (PBMC) to monitor the immune response after vaccination. Because human blood is compris...
ORGANISM(S): Homo sapiens (Human) 
2015-01-08 | PXD001657 | Pride
Human Systems vaccinology Vaccine response Immune response Blood Immune cells Quantitative proteomics Itraq Tiv 
TranscriptomicsTranscription profiling of mouse skin carcinogenesis in FVB/N and Tg.Ac mice
Female FVB/N and Tg.Ac (hemizygotes) mice 3-5 weeks of age were purchased from Harlan UK and Taconic UK, respectively. The mice were contained in an isolator and maintained at 19C with 50% relative humidity and a 12-hour light-dark cycle. Following a 1 week acclimatisation period the dorsal skin o...
ORGANISM(S): Mus musculus 
2005-10-01 | E-MEXP-188 | biostudies-arrayexpress
TranscriptomicsGenomeTiling
Samples were purchased from Clontech as mRNA. Hybridization material was generated through a random-priming amplification procedure (RP-AMP) using primers with a random sequence at the 3' end and a fixed motif at the 5' end. shDNP256 (first strand synthesis): 5'- TAG ATG CTG TTG NNN NNN NNN -3' sh...
ORGANISM(S): Homo sapiens 
2004-03-03 | E-GEOD-1097 | biostudies-arrayexpress
TranscriptomicsAn ABA response regulator unique to basal land plants required for the acquisition of desiccation tolerance
Purpose: The plant hormone abscisic acid (ABA) coordinates responses leading to desiccation tolerance in all land plants. RNA-seq was employed to obtain differential expression data in response to ABA, dehydration and mannitol treatments in wild-type tissue. This was compared against the targeted ge...
ORGANISM(S): Physcomitrella patens 
2016-07-25 | E-GEOD-72583 | biostudies-arrayexpress
Unknown"What do you mean I can't have a doctor? this is Canada!" - a qualitative study of the myriad consequences for unattached patients awaiting primary care attachment.
Not available
S-EPMC8966849 | biostudies-literature
TranscriptomicsRNAseq profiling of a lpp1663 mutant compared to its isogenic parent Legionella pneumophila strain Paris
Comparaison of the transcriptional profile of mutant of the lpp1663 gene and the parent strain Legionella pneumophila strain Paris. lpp1663 codes for a protein with a ProQ domain (PFAM PF04352). A mutant of this gene was obtained by deleting the lpp1663 ORF and replacing it with a gene confering res...
ORGANISM(S): Legionella pneumophila 
2020-09-01 | E-MTAB-4095 | biostudies-arrayexpress
UnknownDifferent clades and traits yield similar grassland functional responses.
Not available
S-EPMC5278461 | biostudies-literature
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