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TranscriptomicsDiurnal gene expression in Populus wild type and lhy RNAi line 10
Previous studies have shown that a considerable proportion of the Arabidopsis genome cycles under circadian and/or diurnal conditions (Edwards et al., 2006 PMID: 16473970, Blaesing et al., 2005 PMID 16299223). It is likely that the correct phasing of gene expression plays an important role in improv...
ORGANISM(S): Populus tremula x Populus tremuloides 
2018-03-13 | E-MTAB-4516 | biostudies-arrayexpress
GenomicsICGC Oesophageal Adenocarcinoma sequence data - mobile_elements - samples
Samples from Edwards et al 2015 - doi:10.1186/s12864-015-1685-z
EGAD00001001048 | EGA
MetabolomicsMetabolic profiling of rheumatoid arthritis neutrophils reveals altered energy metabolism that is not affected by JAK inhibition
Neutrophils play a key role in the pathophysiology of rheumatoid arthritis (RA) where release of ROS and proteases directly causes damage to joints and tissues. Neutrophil function is directly affected by Janus Kinase (JAK) inhibitor drugs, including tofacitinib and baricitinib, which are clinically...
2023-07-11 | MTBLS4766 | MetaboLights
ProteomicsA Cell-based Systems Biology Assessment of Human Blood to Monitor Immune Responses After Influenza Vaccination
Systems biology is an approach to comprehensively study complex interactions within a biological system. Most published systems vaccinology studies have utilized whole blood or peripheral blood mononuclear cells (PBMC) to monitor the immune response after vaccination. Because human blood is compris...
ORGANISM(S): Homo sapiens (Human) 
2015-01-08 | PXD001657 | Pride
Human Systems vaccinology Vaccine response Immune response Blood Immune cells Quantitative proteomics Itraq Tiv 
TranscriptomicsTranscription profiling of mouse skin carcinogenesis in FVB/N and Tg.Ac mice
Female FVB/N and Tg.Ac (hemizygotes) mice 3-5 weeks of age were purchased from Harlan UK and Taconic UK, respectively. The mice were contained in an isolator and maintained at 19C with 50% relative humidity and a 12-hour light-dark cycle. Following a 1 week acclimatisation period the dorsal skin o...
ORGANISM(S): Mus musculus 
2005-10-01 | E-MEXP-188 | biostudies-arrayexpress
TranscriptomicsGenomeTiling
Samples were purchased from Clontech as mRNA. Hybridization material was generated through a random-priming amplification procedure (RP-AMP) using primers with a random sequence at the 3' end and a fixed motif at the 5' end. shDNP256 (first strand synthesis): 5'- TAG ATG CTG TTG NNN NNN NNN -3' sh...
ORGANISM(S): Homo sapiens 
2004-03-03 | E-GEOD-1097 | biostudies-arrayexpress
ModelsPokhilko2012_CircClock_RepressilatorFeedbackloop
This model is from the article: The clock gene circuit in Arabidopsis includes a repressilator with additional feedback loops Pokhilko A, Fernández AP, Edwards KD, Southern MM, Halliday KJ, Millar AJ. Mol Syst Biol.2012 Mar 6;8:574. 22395476, Abs...
2024-09-02 | BIOMD0000000412 | BioModels
TranscriptomicsAn ABA response regulator unique to basal land plants required for the acquisition of desiccation tolerance
Purpose: The plant hormone abscisic acid (ABA) coordinates responses leading to desiccation tolerance in all land plants. RNA-seq was employed to obtain differential expression data in response to ABA, dehydration and mannitol treatments in wild-type tissue. This was compared against the targeted ge...
ORGANISM(S): Physcomitrella patens 
2016-07-25 | E-GEOD-72583 | biostudies-arrayexpress
ModelsPokhilko2010_CircClock
This a model from the article: Data assimilation constrains new connections and components in a complex, eukaryotic circadian clock model. Pokhilko A, Hodge SK, Stratford K, Knox K, Edwards KD, Thomson AW, Mizuno T, Millar AJ. Mol Syst Biol.2010 Sep 21;6:416. 2...
2024-09-02 | BIOMD0000000273 | BioModels
Unknown"What do you mean I can't have a doctor? this is Canada!" - a qualitative study of the myriad consequences for unattached patients awaiting primary care attachment.
Not available
S-EPMC8966849 | biostudies-literature
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