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TranscriptomicsTrivalent Inactivated Influenza Vaccine (TIV) and Live Attenuated Influenza Vaccine (LAIV) Induce Different B cell and Transcriptional Responses in Children
LAIV and TIV are effective for prevention of influenza infection in children, but the mechanisms associated with protection are still not well defined. We analyzed the differences in B cell responses and transcriptional profiles. Compared to baseline, LAIV elicited a significant increase in naM-CM-/...
ORGANISM(S): Homo sapiens 
2014-03-31 | E-GEOD-52005 | biostudies-arrayexpress
TranscriptomicsTime Course of Adults Vaccinated with Influenza TIV Vaccine during 2011/12 Flu Season
Systems approaches have been used to describe molecular signatures driving immunity to influenza vaccination in humans. Whether such signatures are similar across multiple seasons, and in diverse populations is unknown. We applied systems approaches to study immune responses in young and, elderly su...
ORGANISM(S): Homo sapiens 
2016-01-05 | E-GEOD-74816 | biostudies-arrayexpress
TranscriptomicsTime Course of Adults Vaccinated with Influenza TIV Vaccine during 2009/10 Flu Season
Systems approaches have been used to describe molecular signatures driving immunity to influenza vaccination in humans. Whether such signatures are similar across multiple seasons, and in diverse populations is unknown. We applied systems approaches to study immune responses in young and, elderly su...
ORGANISM(S): Homo sapiens 
2015-12-16 | E-GEOD-74811 | biostudies-arrayexpress
UnknownSafety and Immunogenicity of Full-Dose Trivalent Inactivated Influenza Vaccine (TIV) Compared With Half-Dose TIV Administered to Children 6 Through 35 Months of Age.
Not available
S-EPMC4554205 | biostudies-literature
TranscriptomicsTime Course of Adults Vaccinated with Influenza TIV Vaccine during 2010/11 Flu Season (FluCenter cohort)
Systems approaches have been used to describe molecular signatures driving immunity to influenza vaccination in humans. Whether such signatures are similar across multiple seasons, and in diverse populations is unknown. We applied systems approaches to study immune responses in young and, elderly su...
ORGANISM(S): Homo sapiens 
2015-12-16 | E-GEOD-74815 | biostudies-arrayexpress
TranscriptomicsFACS-sorted cells from Young Adults Vaccinated with Influenza TIV or LAIV Vaccines during 2008/09 Flu Season
Systems vaccinology has emerged as an interdisciplinary field that combines systems wide measurements and network and predictive modeling applied to vaccinology. Here we used the systems vaccinology approach to study the molecular mechanisms underlying the innate responses to the trivalent inactivat...
ORGANISM(S): Homo sapiens 
2011-07-10 | E-GEOD-29618 | biostudies-arrayexpress
TranscriptomicsTrivalent Inactivated Influenza Vaccine (TIV) and Live Attenuated Influenza Vaccine (LAIV) Induce Different B cell and Transcriptional Responses in Children
LAIV and TIV are effective for prevention of influenza infection in children, but the mechanisms associated with protection are still not well defined. We analyzed the differences in B cell responses and transcriptional profiles. Compared to baseline, LAIV elicited a significant increase in naïve, m...
ORGANISM(S): Homo sapiens 
2014-03-31 | GSE52005 | GEO
TranscriptomicsTime Course of Young Adults Vaccinated with Influenza TIV Vaccine during 2007/08 Flu Season
Systems vaccinology has emerged as an interdisciplinary field that combines systems wide measurements and network and predictive modeling applied to vaccinology. Here we used the systems vaccinology approach to study the molecular mechanisms underlying the innate responses to the trivalent inactivat...
ORGANISM(S): Homo sapiens 
2011-07-10 | E-GEOD-29614 | biostudies-arrayexpress
TranscriptomicsTime Course of Young Adults Vaccinated with Influenza TIV Vaccine during 2008/09 Flu Season
Systems vaccinology has emerged as an interdisciplinary field that combines systems wide measurements and network and predictive modeling applied to vaccinology. Here we used the systems vaccinology approach to study the molecular mechanisms underlying the innate responses to the trivalent inactivat...
ORGANISM(S): Homo sapiens 
2011-07-10 | E-GEOD-29617 | biostudies-arrayexpress
TranscriptomicsTime Course of Young Adults Vaccinated with Influenza TIV Vaccine during 2008/09 Flu Season
Systems vaccinology has emerged as an interdisciplinary field that combines systems wide measurements and network and predictive modeling applied to vaccinology. Here we used the systems vaccinology approach to study the molecular mechanisms underlying the innate responses to the trivalent inactivat...
ORGANISM(S): Homo sapiens 
2011-07-10 | GSE29617 | GEO
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