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TranscriptomicsGene-expression profile of the response to E. coli (k2bh2) infection in the bovine udder
Mastitis in dairy cows is one of the most costly and prevalent diseases affecting dairy cows world wide. Insight in the molecular regulation of the host immune response to an E. coli infection, could help to develop new strategies to prevent cattle from E. coli infection. Here we performed a gene-ex...
ORGANISM(S): Bos taurus 
2011-03-01 | E-GEOD-24217 | biostudies-arrayexpress
MetabolomicsMetabolic profiling of rheumatoid arthritis neutrophils reveals altered energy metabolism that is not affected by JAK inhibition
Neutrophils play a key role in the pathophysiology of rheumatoid arthritis (RA) where release of ROS and proteases directly causes damage to joints and tissues. Neutrophil function is directly affected by Janus Kinase (JAK) inhibitor drugs, including tofacitinib and baricitinib, which are clinically...
2023-07-11 | MTBLS4766 | MetaboLights
TranscriptomicsThe Wnt/β-catenin-signaling pathway is modulated by androgen ablation therapy for advanced clinical prostate cancer and contributes to androgen independent cell growth
Androgen ablation therapy (AAT) is standard treatment for locally-advanced/metastatic prostate cancer (PCa). Many patients develop castration-resistance (CRPCa) after ~2-3 years, with a poor prognosis. The molecular mechanisms underlying CRPCa progression are unclear. mRNA-Seq was performed on tu...
ORGANISM(S): Homo sapiens 
2013-10-07 | E-GEOD-48403 | biostudies-arrayexpress
UnknownConsortium analysis of 7 candidate SNPs for ovarian cancer.
Not available
S-EPMC2667795 | biostudies-literature
UnknownValidating genetic risk associations for ovarian cancer through the international Ovarian Cancer Association Consortium.
Not available
S-EPMC2634713 | biostudies-literature
UnknownCommon variants at 19p13 are associated with susceptibility to ovarian cancer.
Not available
S-EPMC3125495 | biostudies-literature
UnknownAllele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution.
Not available
S-EPMC5720478 | biostudies-literature
UnknownMeta-analysis of individual-patient data from EVAR-1, DREAM, OVER and ACE trials comparing outcomes of endovascular or open repair for abdominal aortic aneurysm over 5 years.
Not available
S-EPMC5299468 | biostudies-literature
UnknownGWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.
Not available
S-EPMC3693183 | biostudies-literature
UnknownTrends in Mortality in People With HIV From 1999 through 2020: A Multicohort Collaboration.
Not available
S-EPMC11581700 | biostudies-literature
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