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Comparison of gene expression of the osteoclast precursor myeloid blast seeded on plastic and on bone, primed with M-CSF for 4 days and culture with M-CSF and RANKL for 1 day. Osteoclasts and macrophages share progenitors that must receive decisive lineage signals driving them into their respective ...
ORGANISM(S): Mus musculus 
Samples from Edwards et al 2015 - doi:10.1186/s12864-015-1685-z
This a model from the article: A mathematical model of bone remodeling dynamics for normal bone cell populations and myeloma bone disease Bruce P Ayati, Claire M Edwards, Glenn F Webb and John P Wikswo. Biology Direct2010 Apr 20;5(28). 20406449, ...
2024-09-02 | BIOMD0000000401 | BioModels
This a model from the article: A mathematical model of bone remodeling dynamics for normal bone cell populations and myeloma bone disease Bruce P Ayati, Claire M Edwards, Glenn F Webb and John P Wikswo. Biology Direct2010 Apr 20;5(28). 20406449, ...
2024-09-02 | BIOMD0000000402 | BioModels
This a model from the article: A mathematical model of bone remodeling dynamics for normal bone cell populations and myeloma bone disease Bruce P Ayati, Claire M Edwards, Glenn F Webb and John P Wikswo. Biology Direct2010 Apr 20;5(28). 20406449, ...
2024-09-02 | BIOMD0000000403 | BioModels
Examine the distribution of KDM1A and the histone H3K4me2 mark on chromatin following treatment with two distinct classes of KDM1A inhibitors - an irreversible inhibitor (RN-1) and a reversible inhibitor (GSK690) 15 samples total from two treated cell lines - 9 from Kasumi-1 and 6 from SKNO-1. Cont...
ORGANISM(S): Homo sapiens 
Chromosomal instability is central to the process of carcinogenesis. The detection of somatic chromosomal alterations in small premalignant lesions genome-wide remains challenging since sample heterogeneity dilutes the aberrant cell information. We introduced an analytic metric termed "delta-θ&...
ORGANISM(S): Homo sapiens 
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