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ProteomicsBiomolecular condensation orchestrates clathrin-mediated endocytosis in plants
Clathrin-mediated endocytosis is an essential cellular internalisation pathway involving the dynamic assembly of clathrin and accessory proteins to form membrane-bound vesicles. The evolutionarily ancient TSET/TPLATE complex (TPC) plays an essential, but not well-defined role in endocytosis in plant...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2023-12-07 | PXD045068 | Pride
Ap-ms Arabidopsis Clathrin-mediated endocytosis Tplate complex Ateh1 
ProteomicsMapping the protein interaction network of adaptor protein complex in Arabidopsis identifies P34 as a common stability regulator
Adaptor protein (AP) complexes are evolutionarily conserved vesicle transport regulators that recruit coat proteins, membrane cargos and coated vesicle accessory proteins. Since in plants endocytic and post-Golgi trafficking intersect at the trans-Golgi network, unique mechanisms for sorting cargos ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2023-12-07 | PXD035454 | Pride
Ap-ms Arabidopsis Turboid Proximity labeling Adaptor complex Tap Interaction network 
ProteomicsMolecular architecture of the endocytic TPLATE complex – part1 TAP/BS3 cross-linking dataset
Eukaryotic cells rely on endocytosis to regulate their plasma membrane proteome and lipidome. Most eukaryotic groups, except fungi and animals, have retained the evolutionary ancient TSET complex as endocytic regulator. Unlike other coatomer complexes, structural insight into TSET is lacking. Here, ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2021-03-04 | PXD023022 | Pride
Tset Arabidopsis Structure Tplate complex Bs3 cross-linking 
ProteomicsThe endocytic TPLATE complex internalizes ubiquitinated plasma membrane cargo
Endocytosis controls the perception of stimuli by modulating protein abundance at the plasma membrane. In plants, clathrin-mediated endocytosis is the most prominent internalization pathway and relies on two multimeric adaptor complexes, the AP-2 and the TPLATE complex (TPC). Ubiquitination is a wel...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2023-03-11 | PXD035444 | Pride
Ap-ms Arabidopsis Tplate complex Endocytosis 
ProteomicsMolecular architecture of the endocytic TPLATE complex – part2 IP-MS dataset
Eukaryotic cells rely on endocytosis to regulate their plasma membrane proteome and lipidome. Most eukaryotic groups, except fungi and animals, have retained the evolutionary ancient TSET complex as endocytic regulator. Unlike other coatomer complexes, structural insight into TSET is lacking. Here, ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2021-03-04 | PXD023051 | Pride
Tset Arabidopsis Structure Ip-ms Tplate complex 
ProteomicsA MULTI-DIMENSIONAL INTERACTOMICS VIEW ON THE PLANT SNRK1 KINASE COMPLEX REVEALS A KEY REGULATORY ROLE FOR THE CLASS II T6P SYNTHASE-LIKE PROTEINS – part2 TurboID-MS dataset
The plant SNF1-related kinase (SnRK1) plays a central role in energy and metabolic homeostasis. SnRK1 controls growth upon activation by energy-depleting stress conditions, while also monitoring key developmental transitions and nutrient allocation between source and sink tissues. To obtain deeper i...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2022-08-30 | PXD030048 | Pride
Arabidopsis Turboid Proximity labeling Snrk1 complex 
ProteomicsArabidopsis CASEIN KINASE 2 controls Aluminium toxicity and phosphate deficiency through control of the DNA damage response
Aluminum (Al) toxicity and phosphate (Pi) limitation are widespread chronic abiotic and mutually enhancing stresses that profoundly affect crop yield. Both stresses causes a strong inhibition of root growth due to a progressive exhaustion of the stem cell niche. Here we report on a CASEIN KINASE 2 (...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2021-03-29 | PXD018727 | Pride
Phosphate limitation Arabidopsis Aluminium toxicity Casein kinase 2 Dna damage response 
ProteomicsThe LUMINIDEPENDENS protein is a general repressor of transcription in Arabidopsis
Genomic integrity is constantly challenged by transcription/replication conflicts (TRCs), a major source of replication stress (RS) and instability across all life forms. While extensive studies have uncovered TRC resolution mechanisms in animals, yeast, and prokaryotes, their counterparts in plants...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-11-17 | PXD065507 | Pride
Luminidependens Ap-ms Arabidopsis 
ProteomicsTraB is a component of the ER-Mitochondrial contact site regulating ER-Mitochondrial interaction and mitophagy
ER-mitochondria contact sites (EMCSs) are important for mitochondrial function. Here, we have identified a EMCS complex, comprising a family of uncharacterised mitochondrial outer- membrane proteins, TraB1, TraB2 and the ER protein, VAP27-1. In Arabidopsis, there are three TraB isoforms and the t...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2022-08-30 | PXD036285 | Pride
Trab / vap27 / tap / membrane contact sites / endoplasmic reticulum / mitochondria / autophagy / mitophagy / arabidopsis 
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