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TranscriptomicsFrequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line
Epigenetic reprogramming is commonly observed in cancer, and is hypothesized to involve multiple mechanisms, including DNA methylation and Polycomb repressive complexes (PRCs). Here we devise a new experimental and analytical strategy using customized high density tiling arrays to investigate coordi...
ORGANISM(S): Homo sapiens 
2008-08-07 | E-GEOD-12334 | biostudies-arrayexpress
ProteomicsMimicking tumor cell heterogeneity of colorectal cancer in a patient-derived organoid-fibroblast model
Patient derived organoids (PDOs) have been established as a 3D culture model which closely recapitulates the in vivo tumor biology. However, one limitation of this culture model is the lack of tumor microenvironment which has a significant role in tumor progression and drug response. To address this...
ORGANISM(S): Homo sapiens (Human) 
2023-03-14 | PXD032047 | Pride
Cancer associated fibroblast Normal fibroblast Colorectal cancer 
UnknownRevealing viral and cellular dynamics of HIV-1 at the single-cell level during early treatment periods.
Not available
S-EPMC10326345 | biostudies-literature
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