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TranscriptomicseIF3 PAR-CLIP in 293T cells
Regulation of protein synthesis is fundamental for all aspects of eukaryotic biology by controlling development, homeostasis, and stress responses. The 13-subunit, 800-kDa eukaryotic initiation factor 3 (eIF3) organizes initiation factor and ribosome interactions required for productive translation....
ORGANISM(S): Homo sapiens 
2015-04-06 | E-GEOD-65004 | biostudies-arrayexpress
ProteomicseIF3 subunit-specific mRNA selectivity profiling reveals eIF3k as a cancer-relevant regulator of ribosome content
eIF3, whose subunits are frequently overexpressed in cancer, regulates mRNA translation from initiation to termination, but mRNAeIF3, whose subunits are frequently overexpressed in cancer, regulates mRNA translation from initiation to termination, but mRNA-selective functions of individual subunits ...
ORGANISM(S): Homo sapiens (Human) 
2023-03-14 | PXD034084 | Pride
Eif3 
GenomicsLuteibacter flocculans strain:EIF3
Luteibacter flocculans strain:EIF3 Genome sequencing
PRJNA669578 | ENA
Transcriptomicsm6A in 5’ untranslated regions promotes cap-independent translation of mRNA
N6-methyladenosine (m6A) is a widespread internal RNA modification whose function is poorly understood. Here we report that m6A residues within the 5'UTR promote a novel form of cap-independent translation which is mediated through an interaction between m6A residues and the translation initiation f...
ORGANISM(S): Homo sapiens 
2015-10-26 | E-GEOD-73405 | biostudies-arrayexpress
TranscriptomicseIF3a in Urinary Bladder Cancer M-bM-^@M-^S in vivo and in vitro insights
The eukaryotic translation initiation factor (eIF) 3a is described in various tumor entities as potential tumor marker involved in development and progression of cancer. eIF3a is the largest subunit of the eIF3 complex, a key functional entity in 80S establishment and translation initiation. We hypo...
ORGANISM(S): Homo sapiens 
2014-08-12 | E-GEOD-45636 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis eif3h mutants vs. wild type
Microarray comparisons of transcript level in wild-type Arabidopsis and eif3h mutant plants. Goal:; To detect any change in transcript level between WT and eif3h mutant. BACKGROUND: The eukaryotic translation initiation factor eIF3 has multiple roles during the initiation of translation of cytoplasm...
ORGANISM(S): Arabidopsis thaliana 
2008-06-14 | E-GEOD-6025 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis polysomal and non-polysomal RNA samples isolated from 10-day-old wild-type and eif3h mutant plants
Microarray comparisons of polysome loading in wild-type Arabidopsis and eif3h mutant; Goal: ; To find the target mRNAs that are translationally regulated by eIF3h. BACKGROUND: The eukaryotic translation initiation factor eIF3 has multiple roles during the initiation of translation of cytoplasmic mRN...
ORGANISM(S): Arabidopsis thaliana 
2008-06-14 | E-GEOD-6024 | biostudies-arrayexpress
OthereIF3 PAR-CLIP in 293T cells
Regulation of protein synthesis is fundamental for all aspects of eukaryotic biology by controlling development, homeostasis, and stress responses. The 13-subunit, 800-kDa eukaryotic initiation factor 3 (eIF3) organizes initiation factor and ribosome interactions required for productive translation....
ORGANISM(S): Homo sapiens 
2015-04-06 | GSE65004 | GEO
ProteomicseIF3 complex components in HEK293T cells
We assessed the eIF3 complex components in eIF3D-V5 tag knock-in HEK293T cells by label-free mass spectrometry after tag pull-down assay.
ORGANISM(S): Homo Sapiens (human) 
2021-05-05 | PXD025794 | JPOST Repository
GenomicseIF3 interactions with miRNAs involved in translational control of early T cell activation
eIF3 interactions with miRNAs involved in translational control of early T cell activation
PRJNA1454361 | ENA
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