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BACKGROUND & AIMS: Micronutrient deficiency (MND) (ie, lack of vitamins and minerals) during pregnancy is a major public health concern. Historically, studies have considered micronutrients in isolation; however, MNDs rarely occur alone. The impact of co-occurring MNDs on pu...

2024-10-18 | MTBLS3476 | MetaboLights

Background: Polystyrene microplastics (PS-MPs) are degradation products of plastics that are prevalent in the environment. Recent studies have established a significant correlation between exposure to PS-MPs and the incidence of cardiovascular diseases (CVD). Objective: This study aims to investi...

2026-08-16 | MTBLS14514 | MetaboLights

Oxidative stress and ferroptosis are central to the pathogenesis of many diseases, including those characterized by intestinal damage, where excessive lipid peroxidation and iron accumulation trigger cellular dysfunction. In this study, we investigate the protective effects of astaxanthin (ASTA),...

2025-10-14 | MTBLS13140 | MetaboLights

Ecologically derived synthetic communities can provide robust plant benefits, yet generalizable rules for assembling multifunctional consortia remain limited. We hypothesized that a “top-down” community assembled from an ecological core would yield complementary functions and resilience superior ...

2025-09-22 | MTBLS13022 | MetaboLights

Pathogenic bacteria's metabolic adaptation for survival and proliferation within hosts is a crucial aspect of bacterial pathogenesis. Here, we demonstrate that citrate, the first intermediate of the tricarboxylic acid (TCA) cycle, plays a key role as a regulator of gene expression in Staphylococc...

2024-04-26 | MTBLS4276 | MetaboLights
Iron-sulfur (Fe-S) clusters play an essential role in plants as protein co-factors mediating diverse electron transfer reactions. Because they can react with oxygen to form reactive oxygen species (ROS) and cause cellular damage, the biogenesis of Fe-S clusters is highly regulated. A newly discovere...
ORGANISM(S): Arabidopsis Thaliana 
2021-01-24 | PXD015447 | panorama
Analysis of livers from 74-day old male rats fed vitamin A sufficient or vitamin A deficient diet for 53 days. Either 10ug or 2ug of total RNA used in standard Affymetrix protocol
ORGANISM(S): Rattus norvegicus 
A bioinformatic approach to identify targets of microRNA in cancer. Keywords: Patient sample study Samples GSM413237-GSM413270: Total RNA from 17 RCC tumors and 17 corresponding non-tumor samples was hybridized against a common reference RNA (Perou CM, Sorlie T, Eisen MB, et al. Molecular portraits...
ORGANISM(S): Homo sapiens 
The study examined the proteins that were specifically carbonylated in the wild-type seedlings exposed to iron-deficiency conditions. The results indicated that proteins were differentially carbonylated between the wild type and the triple ferritin mutant Fer1-3-4 in the leaves, stem, and flowers in...
ORGANISM(S): Arabidopsis Thaliana (ncbitaxon:3702) 
2022-10-14 | MSV000090535 | MassIVE
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