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TranscriptomicsDifferentially regulated genes in control and c-myc N-myc deficient LT-HSCs
Analysis of HSCs from control and c-myc N-myc deficient long-term hematopoietic stem cells. HSCs lacking both c-myc and N-myc display increased apoptosis rates. Data provide insight into the molecular changes occuring upon complete loss of Myc activity, clarifying the resulting apoptotic mechanism a...
ORGANISM(S): Mus musculus 
2009-02-20 | E-GEOD-12467 | biostudies-arrayexpress
Transcriptomicsdmyc overexpression 7h and 14h
Fly strains: All transgenes are P[+] in w strains. w+;+;Act 5c > CD2 > GAL4 UAS-GFP (Neufeld et al. 1998 ); y w hs-FLP122; +; UAS-dMyc (Zaffran et al. 1998 ). y w hs-FLP122; +; +. Adult flies and larvae were raised in regular fly food consisting of cornmeal and molasses at 25°C. Larvae overexpress...
ORGANISM(S): Drosophila melanogaster 
2010-05-27 | E-GEOD-2073 | biostudies-arrayexpress
TranscriptomicsMyc influences embryonic stem cell pluripotency by regulating miRNAs
Previous studies have demonstrated that the c-Myc transcription factor regulates and cooperates with oncogenic miRNAs to accelerate tumorigenesis. Much recent work has shown that Myc plays an important role in stem cell pluripotency. These findings have prompted us to determine whether Myc regulates...
ORGANISM(S): Mus musculus 
2010-06-25 | E-GEOD-13127 | biostudies-arrayexpress
UnknownGenetic requirement for Mycl and efficacy of RNA Pol I inhibition in mouse models of small cell lung cancer.
Not available
S-EPMC4911928 | biostudies-literature
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