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Pigment Epithelium-Derived Factor (PEDF) has recently been identified as a factor that is significantly upregulated in late-stage osteoarthritic cartilage in which chondrocytes are confronted with terminal differentiation and cell death. Since PEDF is known to induce cell death of endothelial cells,...
ORGANISM(S): Homo sapiens 
MicroRNAs play a vital role in the process of tumorigenesis. To identify and characterize miRNA Expression in renal cell cancer, we performed microarray based screening of miRNA expression profiles in clear cell, papillary type 1 and papillary type 2 renal cell cancer. We selected cases of confirmed...
ORGANISM(S): Homo sapiens 
MicroRNAs are small RNA molecules of about 21-25 nucleotides that regulate gene expression via posttranscriptional inhibition of protein synthesis. They play a vital role in the process of tumorigenesis. To identify and characterize the diagnostic potential of miRNAs in prostate cancer, a leading ca...
ORGANISM(S): Homo sapiens 
Coarctation of the aorta (CoA) accounts for 5-8% of all congenital heart defects. CoA can be detected in up to 20% of patients with Ullrich-Turner syndrome (UTS), in which a part or all of one of the X chromosomes is absent. The etiology of non-syndromic CoA is poorly understood. In the present wor...
ORGANISM(S): Homo sapiens 
Coarctation of the aorta (CoA) accounts for 5-8% of all congenital heart defects. CoA can be detected in up to 20% of patients with Ullrich-Turner syndrome (UTS), in which a part or all of one of the X chromosomes is absent. The etiology of non-syndromic CoA is poorly understood. In the present wor...
ORGANISM(S): Homo sapiens 
We performed RNA-seq experiments on 14 samples to identify differential expressed genes between MelanA- and caIKK-treated monocyte-derived dendritic cells (DCs). DCs electroporated with RNA encoding melanoma antigen recognized by T cells 1 (MelanA) were used as control, and DCs electroporated with R...
ORGANISM(S): Homo sapiens 
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