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ProteomicsA viral ORFeome library for systems-level genetic dissection of host-pathogen interactions
Virological research has traditionally focused on individual viruses or viral families. Advances in DNA synthesis now allow large-scale construction of individual gene products, enabling systematic exploration of the virome. Here, we developed a barcoded library of ~12,000 viral open reading frames ...
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD077910 | Pride
Yldv 151r Virome 
ProteomicsA viral ORFeome library for systems-level genetic dissection of host-pathogen interactions
Virological research has traditionally focused on individual viruses or viral families. Advances in DNA synthesis now allow large-scale construction of individual gene products, enabling systematic exploration of the virome. Here, we developed a barcoded library of ~12,000 viral open reading frames ...
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD077768 | Pride
Virome Mc162r Yldv 151r Tmt Mhc 
TranscriptomicsVGLL4 is a novel regulator of survival in human embryonic stem cells
Human embryonic stem cells (hESCs) are maintained in a self-renewing state by an interconnected network of mechanisms that sustain pluripotency, promote proliferation and survival, and prevent differentiation. We sought to find novel genes that could contribute to one or more of these processes by u...
ORGANISM(S): Homo sapiens 
2013-12-01 | E-GEOD-44590 | biostudies-arrayexpress
TranscriptomicsA sumoylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis
Myc is an oncogenic transcription factor frequently dysregulated in human cancer. To identify pathways supporting the Myc oncogenic program, we employed a genome-wide RNAi screen for Myc-synthetic-lethal (MySL) genes and uncovered a role for the SUMO-activating-enzyme (SAE1/2). Loss of SAE1/2 enzyma...
ORGANISM(S): Homo sapiens 
2011-12-08 | E-GEOD-34055 | biostudies-arrayexpress
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