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MetabolomicsLongitudinal multi-omics reveals subset-specific mechanisms underlying irritable bowel syndrome

The gut microbiome has been implicated in multiple human chronic gastrointestinal (GI) disorders. Determining its mechanistic role in disease has been difficult due to apparent disconnects between animal and human studies and lack of an integrated multi-omics view of disease-specific physiologica...

2020-09-08 | MTBLS1396 | MetaboLights
UnknownEPISCORE: cell type deconvolution of bulk tissue DNA methylomes from single-cell RNA-Seq data.
Not available
S-EPMC7650528 | biostudies-literature
UnknownAssessing knowledge, attitudes, willingness, and barriers to Pneumococcal vaccination among Canadian older adults: a cross-sectional survey.
Not available
S-EPMC12870518 | biostudies-literature
UnknownFinancial Integration's Impact On Care Delivery And Payment Reforms: A Survey Of Hospitals And Physician Practices.
Not available
S-EPMC7849626 | biostudies-literature
TranscriptomicsExpression data for 2 obese subjects from the SibPair cohort with a deletion on 16p11.2
We report a highly-penetrant form of obesity, initially observed in 31 heterozygous carriers of a 593kb or larger deletion at 16p11.2 from amongst subjects ascertained for cognitive deficits. Nineteen similar deletions were identified from GWAS data in 16053 individuals from 8 European cohorts; such...
ORGANISM(S): Homo sapiens 
2009-12-02 | E-GEOD-19238 | biostudies-arrayexpress
UnknownSepticaemia models using Streptococcus pneumoniae and Listeria monocytogenes: understanding the role of complement properdin.
Not available
S-EPMC4118039 | biostudies-literature
TranscriptomicsSingle cell RNA-seq of human CD8+ T cells binding the IAV HLA-A24/PB1 498-505 tetramer
PBMCs from 4 donors were stained with the influenza A virus HLA-A24/PB1 498-505 tetramer. Two donors (non-LIFT8 and non-LIFT12) showed TCR independent KIR binding to tetramers whereas the other two donors (Non-LIFT14 and Non-LIFT10) showed TCR specific binding. Cells were single-cell sorted on a BD ...
ORGANISM(S): Homo sapiens 
2021-04-08 | E-MTAB-10109 | biostudies-arrayexpress
ProteomicsTissue architectural cues mediated by integrin signaling
Analysis of human or mouse tumor cell lines that target to different organs upon extravasation
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2019-06-21 | MSV000084006 | MassIVE
GenomicsGoT2D: Genetics of Type 2 Diabetes, a study of the the genetic architecture of type 2 diabetes using low pass whole genome sequencing and high density SNP genotyping in 2,657 individuals.
The Genetics of Type 2 Diabetes Consortium (GoT2D) is a collaboration between the University of Michigan, the Broad Institute and the Wellcome Trust Centre for Human Genetics. The overall aim is to extend upon recent efforts, such as genome-wide association studies (GWAS) and large scale meta-analys...
EGAS00001001459 | EGA
UnknownRisk factors for suicidality in Huntington disease: An analysis of the 2CARE clinical trial.
Not available
S-EPMC6448454 | biostudies-literature
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