Sort   by:  
 Page size 
TranscriptomicsTranscription profiling of chicken Bcl6 deficient DT40 B cell line to investigate the targets of Bcl6 which is required for germinal center formation
The transcription factor Bcl6 is required for germinal center formation and deregulated expression of Bcl6 has been observed in lymphomas. To gain insight to the function of Bcl6 in terminal differentiation of B cells to plasma cells and to investigate the targets of Bcl6, we established a Bcl6 defi...
ORGANISM(S): Gallus gallus 
2010-02-17 | E-MEXP-2062 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of spermatogenesis in juvenile mouse testis and analysis of four germ cell deficient mouse models, time series
Temporal study of the first wave of spermatogenesis in juvenile mouse testis and analysis of four germ cell deficient mouse models.
A series of purified testis cell-types (McCarrey libraries)constituting a focussed gene set was exploited to examine gene expression in prepubertal mouse testis. T...
ORGANISM(S): Mus musculus 
2006-08-10 | E-MEXP-571 | biostudies-arrayexpress
no omics definedTranscription profiling of human Vg9/Vd2 T cells after 72h stimulation with HMB-PP in the presence of IL-2, IL-4, or IL-21
Hver2.1.1 microarrays containing ~15,000 genes were used to characterize the gene expression profiles of Vg9/Vd2 T cells upon 72h stimulation with HMB-PP in the presence of IL-2, IL-4, or IL-21.
ORGANISM(S): Homo sapiens 
2007-03-21 | E-MEXP-763 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of C57/BL6J mice at various ages post partum vs a common control adult (8 week) testis RNA from the same strain
Testis RNA from C57/BL6J mice at various ages post partum was compared to a common control consisting of adult (8 week) testis RNA from the same strain. This generates a time course showing the activation of genes on the array across the first wave of spermatogenesis, which can then be correlated w...
ORGANISM(S): Mus musculus 
2004-03-02 | E-MEXP-35 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of HC11 mammary epithelial cell strains stably expressing different variants of the transcriptional regulator megakaryoblastic leukemia-1 (Mkl1)
We have previously shown that HC11 mammary epithelial cells react strongly to the overexpression of megakaryoblastic leukemia-1 (Mkl1) with induction of tenascin-C expression. The present study was designed to find genes co-regulated with tenascin-C by Mkl1 in a SAP domain-dependent manner and witho...
ORGANISM(S): Mus musculus 
2014-02-06 | E-GEOD-44907 | biostudies-arrayexpress
TranscriptomicsIdentification of megakaryoblastic leukemia-1 (Mkl1) target genes in 4T1 mammary carcinoma cells
The present study was designed to identify Mkl1 target genes whose expression requires either the B1 site of Mkl1 and serum response factor (SRF), respectively, or the SAP domain of Mkl1. For this purpose, we obtained the transcriptomes of four stable 4T1 cell lines that either overexpress full leng...
ORGANISM(S): Mus musculus 
2016-07-15 | E-GEOD-59459 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human seminiferous tubules from subfertile/infertile patients undergoing testicular sperm extraction as part of their treatment
43 biopsies were obtained from subfertile/infertile patients undergoing testicular sperm extraction (TESE) as part of their treatment. Labelled cDNAs were compared to a reference normal testis RNA (Ambion).
ORGANISM(S): Homo sapiens 
2007-03-15 | E-MEXP-1019 | biostudies-arrayexpress
UnknownBLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination.
Not available
S-EPMC150347 | biostudies-literature
TranscriptomicsComparison of arf2, gnc gnl and arf2 gnc gnl transcriptomes
We have used Agilent whole genome arrays (v4) to compare the gene expression changes between 10-day-old Arabidopsis wild type seedlings and arf2-8 (Ellis et al., 2005), gnc gnl (Richter et al., 2011) and arf2 gnc gnl mutants (all Col ecotype). Three independent biological samples were prepared for e...
ORGANISM(S): Arabidopsis thaliana 
2013-07-15 | E-GEOD-35730 | biostudies-arrayexpress
TranscriptomicsThe 2HA line of Medicago truncatula has characteristics of an epigenetic mutant that is weakly ethylene insensitive
Background: The Medicago truncatula 2HA seed line is highly embryogenic while the parental line Jemalong rarely produces embryos. The 2HA line was developed from one of the rare Jemalong regenerates and this method for obtaining a highly regenerable genotype in M. truncatula is readily reproducible ...
ORGANISM(S): Medicago truncatula 
2014-06-05 | E-GEOD-58223 | biostudies-arrayexpress
Sort   by:  
 Page size