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TranscriptomicsRNA-seq of human primary hepatocytes treated with FGF19 and CDCA
Primary human hepatocytes were treated with recombinant FGF19 (n=3), CDCA (n=3), endogenously produced FGF19 (n=3), or vehicle controls (n=3+3). Total RNA was harvested and sequenced with a strand-specific paired end RNA-seq protocol.
ORGANISM(S): Homo sapiens 
2021-02-13 | E-MTAB-8627 | biostudies-arrayexpress
TranscriptomicsEpigenetic and transcriptomic signature of aging in human liver [expression]
Gene expression profiling of liver biopsies collected from 33 healthy liver donors ranging from 13 to 90 years old. The Affymetrix HG-U133 Plus 2.0 GeneChip platform was used to evaluate gene-expression. Total RNA (including miRNAs) was extracted using the mirVana miRNA Isolation Kit (Ambion); cDNA ...
ORGANISM(S): Homo sapiens 
2018-09-11 | E-GEOD-107037 | biostudies-arrayexpress
TranscriptomicsLeptin dependent control of testosterone regulated hepatic lipid metabolism
Population based studies have established that androgen deficiency in males correlates with type 2 diabetes, visceral adiposity, and metabolic syndrome. Androgen therapy has been investigated as a possible treatment regime to combat these disorders. However, the molecular mechanism of androgen effec...
ORGANISM(S): Rattus norvegicus 
2012-09-02 | E-GEOD-23941 | biostudies-arrayexpress
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