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GenomicsAffymetrix raw files - samples
Affymetrix 6.0 cel files
EGAD00010000158 | EGA
GenomicsIllumina raw files - samples
Illumina HT 12 IDATS
EGAD00010000160 | EGA
GenomicsZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium.
The telomeric amplicon at 8p12 is common in oestrogen receptor-positive (ER+) breast cancers. Array-CGH and expression analyses of 1172 primary breast tumours revealed that ZNF703 was the single gene within the minimal amplicon and was amplified predominantly in the Luminal B subtype. Amplification ...
EGAS00000000082 | EGA
Genomicsena-DATASET-CRUK-CI-16-05-2016-12:25:56:672-139 - samples
Targeted sequencing of 173 genes in 2433 primary breast tumours. Data includes 2433 tumour samples, 523 adjacent normal (breast) samples and 127 blood samples. Libraries were prepared with Illumina's Nextera custom enrichment kit targetting all the exons of the most frequently mutated breast cance...
EGAD00001002115 | EGA
GenomicsMETABRIC: Data from Pereira et al (2016), The somatic mutation profiles of 2433 breast cancers refine their genomic and transcriptomic landscapes. Nat Comms 7.
The genomic landscape of breast cancer is complex, and inter- and intra-tumour heterogeneity are important challenges in treating the disease. In this study, we sequence 173 genes in 2433 primary breast tumours that have copy number aberration (CNA), gene expression, and long-term clinical follow-u...
EGAS00001001753 | EGA
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