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TranscriptomicsThe Multicopy Gene Sly Represses the Sex Chromosomes in the Male Mouse Germline after Meiosis
Studies of mice with Y chromosome long arm deficiencies suggest that the male-specific region (MSYq) encodes information required for sperm differentiation and postmeiotic sex chromatin repression (PSCR). Several genes have been identified on MSYq, but because they are present in more than 40 copies...
ORGANISM(S): Mus musculus 
2011-05-11 | E-GEOD-29198 | biostudies-arrayexpress
TranscriptomicsThe Multicopy Gene Sly Represses the Sex Chromosomes in the Male Mouse Germline after Meiosis part 2
Studies of mice with Y chromosome long arm deficiencies suggest that the male-specific region (MSYq) encodes information required for sperm differentiation and postmeiotic sex chromatin repression (PSCR). Several genes have been identified on MSYq, but because they are present in more than 40 copies...
ORGANISM(S): Mus musculus 
2011-05-11 | E-GEOD-29200 | biostudies-arrayexpress
TranscriptomicsDeficiency in the multicopy Sycp3-like X-linked genes Slx and Slxl1 causes major defects in spermatid differentiation
The gene Sly is present in multiple copies on the mouse Y chromosome and encodes a protein that is required for the epigenetic regulation of postmeiotic sex chromosome expression. The X chromosome carries two multicopy genes related to Sly: Slx and Slxl1. Here we investigate the role of Slx/Slxl1 us...
ORGANISM(S): Mus musculus 
2011-05-11 | E-GEOD-29197 | biostudies-arrayexpress
GenomicsEGAS00001000515-sc-20141203 - samples
This study aims to define the landscape of somatic mutations in sun exposed human skin by deep sequencing, analyse their frequency and use the data to infer the effect of mutations on proliferating cell behaviour. The frequency of each mutation will reflect the size of the clone of cells in the tiss...
EGAD00001001090 | EGA
GenomicsEGAS00001000603-sc-20140423 - samples
This study aims to define the landscape of somatic mutations in sun exposed human skin by deep sequencing, analyse their frequency and use the data to infer the effect of mutations on proliferating cell behaviour. The frequency of each mutation will reflect the size of the clone of cells in the tiss...
EGAD00001000825 | EGA
GenomicsEGAS00001000860-sc-20150105 - samples
Deep sequencing of two skin biopsies to study the landscape of somatic mutations in human adult tissues.
EGAD00001001123 | EGA
GenomicsUse of Deep Sequencing to Dectect Clonal Mutations In Sun Exposed Skin Epidermis PART2
This study aims to define the landscape of somatic mutations in sun exposed human skin by deep sequencing, analyse their frequency and use the data to infer the effect of mutations on proliferating cell behaviour. The frequency of each mutation will reflect the size of the clone of cells in the tiss...
EGAS00001000603 | EGA
GenomicsUse of deep sequencing to detect clonal mutations in sun exposed human epidermis whole genome
Deep sequencing of two skin biopsies to study the landscape of somatic mutations in human adult tissues.
EGAS00001000860 | EGA
GenomicsUse of Deep Sequencing to Dectect Clonal Mutations In Sun Exposed Skin Epidermis
This study aims to define the landscape of somatic mutations in sun exposed human skin by deep sequencing, analyse their frequency and use the data to infer the effect of mutations on proliferating cell behaviour. The frequency of each mutation will reflect the size of the clone of cells in the tiss...
EGAS00001000515 | EGA
UnknownComparative Analysis of SARS-CoV-2 Antigenicity across Assays and in Human and Animal Model Sera.
Not available
S-EPMC10557678 | biostudies-literature
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