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MetabolomicsMaternal lipid mobilization is essential for embryonic development in a key malaria vector
Lipid metabolism is an essential component in reproductive physiology. While lipid mobilization has been implicated in the growth of Plasmodium falciparum malaria parasites in their Anopheles vectors, the role of this process in the reproductive biology of these mosquitoes remains elusive. Here, we ...
2024-11-05 | MTBLS9881 | MetaboLights
TranscriptomicsExpression profile of zebrafish embryonal rhabdomyosarcoma
Fluorescent-labeled zebrafish RAS-induced embryonal rhabdomyosarcoma (ERMS) were created to facilitate in vivo imaging of tumor-propagating cells, regional tumor heterogeneity, and dynamic cell movements in diverse cellular compartments. Using this strategy, we have identified a molecularly distinc...
ORGANISM(S): Danio rerio 
2012-12-01 | E-GEOD-32425 | biostudies-arrayexpress
TranscriptomicsGene expression data from undifferentiated mouse embryonal carcinoma cell strains (MOE430A and MOE430B)
Gene expression profiles of undifferentiated mouse embryonal carcinoma cell strains (P19, P19CL6, and 4 P19CL6 sublines) were obtained, using Affymetrix GeneChip Mouse Genome 430A and 430B. Heart diseases such as cardiac infarction damage cardiomyocytes and consequently lead to significant loss of t...
ORGANISM(S): Mus musculus 
2011-01-26 | E-GEOD-26875 | biostudies-arrayexpress
TranscriptomicsGene expression data from SOX2 knock-out 2102Ep and NTera-2 human embryonal carcinoma cell lines
SOX2 is an oncogene and a core pluripotency transcription factor. SOX2 has multiple roles in various malignancies, in the maintainance of pluripotency and during various stages of embryonic development. Human embryonal carcinoma cells express SOX2 and the loss of this results in their differentiatio...
ORGANISM(S): Homo sapiens 
2014-08-15 | E-GEOD-59234 | biostudies-arrayexpress
GenomicsSeminoma and embryonal carcinoma footprints identified by analysis of integrated genome-wide epigenetic and expression profiles of germ cell cancer cell lines (ChIP-seq data).
Background: Germ Cell Cancers (GCC), originating from Primordial Germ Cells /gonocytes, are the most common cancer in young men, subdivided in seminoma (SE) and non-seminoma (NS, stem cell component: embryonal carcinoma (EC)). Somatic mutations are rarely found in GCC. It has been proposed that disr...
ORGANISM(S): Homo sapiens 
2014-06-01 | E-GEOD-56450 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human embryonal rhabdomyosarcoma (EMRS) culture to identify PAX3-FKHR regulated genes differentially expressed between alveolar and embryonal rhabdomyosarcomas
The overall goal and objective is to study the degree to which PAX3-FKHR accounts for differences between ARMS and ERMS by expressing a construct (termed P3FK/ER) consisting of PAX3-FKHR joined to the estrogen receptor ligand binding domain in an ERMS cell culture system. Experiment Overall Design: ...
ORGANISM(S): Homo sapiens 
2009-03-14 | E-GEOD-15103 | biostudies-arrayexpress
GenomicsGenomic Screening of Testicular Germ Cell Tumors from Monozygotic Twins
Genomic screening was performed for one family containing MZ twins with testicular germ cell tumors, in order to define alterations associated with risk of tumor development. Copy number alterations were evaluated using array-CGH (4x44K, Agilent Technologies) in one seminoma and one embryonal carcin...
ORGANISM(S): Homo sapiens 
2015-01-31 | E-GEOD-62779 | biostudies-arrayexpress
TranscriptomicsSILENCING OF PNPLA6, THE NEUROPATHY TARGET ESTERASE (NTE) CODIFYING GENE, ALTERS HUMAN NEURODIFFERENTIATION IN VITRO
Neuropathy Target Esterase (NTE) is a protein involved in the development of a polyneuropathy caused by exposure to certain organophosphorus compounds. In vivo and in vitro studies have also associated NTE with embryonic development since NTE null mice embryos are non-viable, and silencing the NTE-c...
ORGANISM(S): Homo sapiens 
2014-10-06 | E-GEOD-55761 | biostudies-arrayexpress
TranscriptomicsGene-expression profile of human embryonic germ cells
Gene-expression profile of human embryonic germ cells (EGCs), primordial germ cells (PGCs), embryonal carcinoma cells (ECCs), pluripotent embryonic stem cells (ESCs) and induced pluripotent stem cells (IPSCs)
ORGANISM(S): Homo sapiens 
2018-06-28 | E-MTAB-6851 | biostudies-arrayexpress
UnknownEpigenetic markers in the embryonal germ cell development and spermatogenesis.
Not available
S-EPMC9948345 | biostudies-literature
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