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TranscriptomicsViral Expression and Molecular Profiling in Liver Tissue versus Microdissected Hepatocytes in Hepatitis B Virus - Associated Hepatocellular Carcinoma
The molecular mechanisms whereby hepatitis B virus (HBV) induces hepatocellular carcinoma (HCC) remain elusive. We used genomic and molecular techniques to investigate host-virus interactions by mapping the entire liver of patients with HCC. We compared the gene signature of whole liver tissue (WLT)...
ORGANISM(S): Homo sapiens 
2014-12-22 | E-GEOD-55092 | biostudies-arrayexpress
TranscriptomicsThree-Dimensional Tumor Profiling Reveals Minimal mRNA Heterogeneity in Esophageal Squamous Cell Carcinoma
We microdissected discrete sub-regions of esophageal squamous cell carcinoma (ESCC) and analyzed the transcriptomes throughout three-dimensional (3D) tumor space. Nine cases were used for TP/TC comparison, five cases were used for 3D analysis, one normal case was set as a control.
ORGANISM(S): Homo sapiens 
2011-11-04 | E-GEOD-33426 | biostudies-arrayexpress
TranscriptomicsIdentification of Unique Therapeutic Targets in Esophageal Squamous Cell Carcinoma
We utilized tissue microdissection and expression microarrays to measure ex vivo gene expression profiles in twelve cases of patient-matched normal basal epithelial cells, normal differentiated squamous epithelium, and cancer. The data set from the precisely-dissected, dividing basal cell layer was ...
ORGANISM(S): Homo sapiens 
2011-05-03 | E-GEOD-29001 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human androgen-dependent and androgen-independent primary prostate cancer tumors
Affymetrix U133A comparison of two groups (10 samples each): untreated (androgen-dependent) primary prostate cancer (Gleasons 5-9) and androgen-independent primary prostate cancer. All samples were microdissected for tumor cells only.
ORGANISM(S): Homo sapiens 
2007-08-25 | E-GEOD-2443 | biostudies-arrayexpress
UnknownLiraglutide and Cardiovascular Outcomes in Type 2 Diabetes.
Not available
S-EPMC4985288 | biostudies-literature
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