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ProteomicsEndogenous human milk proteolysis as a function of pH
The use of human milk products is increasing for high-risk infants. Human milk contains endogenous enzymes that comprise a dynamic proteolytic system; yet, biological properties of these enzymes and their activities in response to variations including pH within infants are unclear. This study was de...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD012748 | Pride
Human Peptide Endogenous proteolysis Q exactive Ph Milk 
UnknownProteolysis controls endogenous substance P levels.
Not available
S-EPMC3716696 | biostudies-literature
UnknownSelective Proteolysis of α-Lactalbumin by Endogenous Enzymes of Human Milk at Acidic pH.
Not available
S-EPMC7231428 | biostudies-literature
ProteomicsAnalysis of endogenous immuno-purification of YAP1 in HEK293A cell lines
Analysis of endogenous immuno-purification of YAP1 in HEK293A cell lines
ORGANISM(S): Homo sapiens (Human) 
2023-03-04 | PXD030137 | Pride
Endogenous apms 
ProteomicsAntibody RING-Mediated Destruction (ARMeD) of endogenous proteins
To help understand the cellular function of a gene the encoding DNA or mRNA transcript can be manipulated and the consequences observed. However, these approaches do not have a direct effect on the protein product of the gene, which is either permanently abrogated or depleted at a rate defined by th...
ORGANISM(S): Homo Sapiens 
2020-05-28 | PXD016193 | panorama
GenomicsProlyl hydroxylase-dependent proteolysis enables the orthogonal hypoxia responses in plants
Prolyl hydroxylase-dependent proteolysis enables the orthogonal hypoxia responses in plants
PRJNA1395612 | ENA
TranscriptomicsTotal and chromatin-associated RNA (totalRNA and chRNA) sequencing experiments upon rapid depletion of endogenous DHX15 or DHX38
To investigate DHX15's functions in splicing QC in human cells, we induced rapid proteolysis-mediated depletion of endogenous DHX15 and DHX38 and performed high-throughput sequencing of totalRNA and chRNA.
ORGANISM(S): Homo sapiens 
2023-10-13 | GSE241712 | GEO
UnknownDoxorubicin induces caspase-mediated proteolysis of KV7.1.
Not available
S-EPMC6162258 | biostudies-literature
ProteomicsTissue protease activity with MALDI MSI
Aberrant protease activity has been implicated in the etiology of various prevalent diseases including neurodegeneration and cancer, in particular metastasis. Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI) has recently been established as a key technology for bio...
ORGANISM(S): Bos Taurus (ncbitaxon:9913) Mus Musculus (ncbitaxon:10090) 
MSV000086102 | MassIVE
TranscriptomicsThe Cushing's disease adipose gene expression profile reveals effects of long term glucocorticoids on adipose tissue lipid, protein and glucose metabolism
Glucocorticoids have major effects on adipose tissue metabolism. To study tissue mRNA expression changes induced by chronic elevated endogenous glucocorticoids, we performed RNA sequencing on subcutaneous adipose tissue from patients with Cushing’s disease (n=5) compared to patients with non-functio...
ORGANISM(S): Homo sapiens 
2015-08-01 | E-GEOD-66446 | biostudies-arrayexpress
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