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MetabolomicsMetabolomic analysis of alfalfa (Medicago sativa L.) root-symbiotic rhizobia responses under alkali stress
Alkaline salts (e.g., NaHCO3 and Na2CO3) causes more severe morphological and physiological damage to plants than neutral salts (e.g., NaCl and Na2SO4) due to differences in pH. The mechanism by which plants respond to alkali stress is not fully understood, especially in plants having symbotic relat...
2018-07-27 | MTBLS481 | MetaboLights
MetabolomicsMetabolomics-Based Analysis of Adaptive Mechanism of Eleutheronema tetradactylum to Low-Temperature Stress

Temperature is a critical environmental factor influencing fish physiology. Eleutheronema tetradactylum is an economically important warm-water species, but its response to long-term cold stress remains unclear. In this study, we exposed juvenile fish to 18 °C for 7 and 14 days and investigated h...

2026-09-08 | MTBLS15459 | MetaboLights
MetabolomicsEffect of heat stress on serum enzyme activity, antioxidant capacity and immune parameter metabolomics datasets in Holstein cows at different growth stages

Global climate change has led to an increase in release of atmospheric CO2 and average daily temperatures, making heat stress a major challenge in dairy farming. The present study aimed to investigate metabolite changes of Holstein cows at different stages. In this experiment, 10 growing heifers,...

2022-08-11 | MTBLS5148 | MetaboLights
MetabolomicsCDK4/6 inhibitor-mediated cell overgrowth triggers an osmotic stress response and chronic p38MAPK activation to promote long-term cell cycle arrest

Cell size and the cell cycle are intrinsically coupled and abnormal increases in cell size are associated with senescence and permanent cell cycle arrest. The mechanism by which overgrowth primes cells to withdraw from the cell cycle remains unknown. We investigate this here using CDK4/6 inhibito...

2025-10-24 | MTBLS5868 | MetaboLights
MetabolomicsChlorogenic acid alters ileal microbiota and metabolites in broilers under immune stress

Immune stress in broilers can cause severe economic losses, chlorogenic acid is an effective plant extract for alleviating immune stress. This study investigates the effect of chlorogenic acid on the intestinal microbiota and metabolites of broilers under immune stress. 312 broilers were randomly...

2025-06-09 | MTBLS11790 | MetaboLights
MetabolomicsIonic homeostasis, carbohydrate metabolism, and oxidative balance underlie wild soybean resistance to low potassium stress

The scarcity of potassium resources in farmland soils poses a major challenge to global food security. Wild soybean (Glycine soja), a valuable wild germplasm related to cultivated soybeans, is known for its high-stress resistance and adaptability. This study comprehensively compares two wild soyb...

2026-04-12 | MTBLS14256 | MetaboLights
MetabolomicsMulti-omics reveals taurine-mediated rumen microbial remodeling mitigates high-starch-diet-induced systemic inflammation and oxidative stress in fattening cattle

Background: With the pursuit of rapid intramuscular fat deposition in beef cattle, basal diets have increasingly shifted toward grain-based, energy-dense formulations. However, high-starch dietary regimens may induce host metabolic dysregulation, which is closely linked to both ruminal microbial ...

2025-09-25 | MTBLS13041 | MetaboLights
MetabolomicsIntegrative transcriptomic, metabolomic, and physiological analyses reveal the root adaptive mechanisms of common vetch (Vicia sativa L.) under drought stress
Drought is a major abiotic stress that limits the productivity and ecological adaptability of leguminous forage crops. As the primary organs that sense soil water deficits, roots play an essential role in plant adaptation to drought. Common vetch (Vicia sativa L.) is an important annual leguminous f...
2026-07-27 | MTBLS15164 | MetaboLights
MetabolomicsPhysiological, Transcriptomic, and Metabolomic Insights into Ammonia-Nitrogen Stress in the Hepatopancreas of Litopenaeus vannamei Acclimated to Low Salinity
High ammonia nitrogen stress markedly decreases the survival rate of Litopenaeus vannamei under low-salinity conditions. Nevertheless, most available studies have primarily focused on the ammonia nitrogen response of small-sized shrimp under single-stressor exposure or normal seawater salinity. The ...
2026-08-13 | MTBLS14736 | MetaboLights
MetabolomicsNovel Adaptive Strategies of Maize Rhizosphere Microbiome Mediated by strain ST-1 Against Vanadium Stress
Vanadium (V) contamination can disrupt plant growth, rhizosphere redox processes, and microbial functions, but how functional bacterial inoculation coordinates rhizosphere ecological adaptation with V behavior in crop systems remains unclear. In this study, a maize pot experiment was conducted to sy...
2026-06-21 | MTBLS14800 | MetaboLights
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