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Endometrial diseases are common gynecological diseases that disorder women of childbearing age and perimenopausal women, including endometrial polyps (EP), endometrial cancer (EC), and endometrial hyperplasia (EH). Clinically, biopsy or imaging methods are usually used to screen and diagnose...

2022-01-14 | MTBLS3444 | MetaboLights

Microplastics and nanoplastics are commonly found in our everyday environments. So far, microplastics and nanoplastics have been detected in various tissues and bodily fluids, including hair, sputum, digestive tissue, lungs, blood, and placental tissue. Although some studies indicate that micropl...

2026-02-05 | MTBLS13850 | MetaboLights

Metabolomic analysis of metabolic differences between NSD1 wild-type and NSD1 knockout endometrial cancer cells

2026-01-21 | MTBLS13567 | MetaboLights
Endometrial cancer (EC) is one of the most common gynecological cancers. Finding biomarkers of EC can support its diagnosis in a non- or minimally-invasive way. In this work, we integrated metabolomics and proteomics for the analysis of multiple types of biosamples to gain a more comprehensive view ...
2022-03-28 | MTBLS3935 | MetaboLights

Metabolic syndrome (MS) is a risk factor for both the development and progression of endometrial cancer (EC); however, the mechanism remains unclear. We found that polyamine metabolites are significantly elevated in the sera and tumor tissues of EC patients with MS (ECWMS). Hyperlipidemia is a cr...

2025-11-08 | MTBLS13106 | MetaboLights
Background: Recurrent implantation failure (RIF) remains a major barrier to successful assisted reproductive technology, given the lack of effective, mechanism-informed interventions to enhance endometrial receptivity. Jiawei Shoutai Wan (pills) (JWSTW), a modified formulation of the classic Shoutai...
2026-03-31 | MTBLS14199 | MetaboLights
MS data of HLA class I and HLA class II ligandome of human endometrial cancer
ORGANISM(S): Homo Sapiens (human) 
sera collected from endometrial cancer patients submitted to direct MS/MS analysis in diluted unprocessed form. MS only analysis of sera has also been performed. files are also available.
ORGANISM(S): Homo Sapiens (human) 
Endometrial cancer is one of the most common gynecologic malignancies, and patients with high grade disease, especially serous papillary subtype (SPEC) are often related to the poor outcomes. Recent genome-wide analyses have revealed that SPEC exhibits gene expression profiles that are distinct from...
ORGANISM(S): Homo sapiens 
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