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ProteomicsDeep quantitative proteomics underlies extensive metabolic reprogramming and cancer-like changes of ectopic endometriotic stromal cells
Endometriosis is a prevalent health condition in women of reproductive age characterized by ectopic growth of endometrial tissue in the extrauterine environment. Thorough understanding of the molecular mechanisms underlying the disease are still lacking and incomplete. We dissect eutopic and ectopic...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-10-22 | MSV000080276 | MassIVE
TranscriptomicsmiRNA expression profiles in endometriotic cyst stromal cells (ECSCs).
To identify the miRNAs which play a role in the development of endometriosis, we explored differentially expressed miRNAs between ECSCs (N=8) and normal endometrial stromal cells (NESCs, n=8) using miRNA microarray. The expression profiles in ECSCs and NESCs were obtained, then the miRNAs were filte...
ORGANISM(S): Homo sapiens 
2013-02-06 | E-GEOD-40186 | biostudies-arrayexpress
ProteomicsDeep quantitative proteomics underlies extensive metabolic reprogramming and cancer-like changes of ectopic endometriotic stromal cells
Endometriosis is a prevalent health condition in women of reproductive age characterized by ectopic growth of endometrial tissue in the extrauterine environment. Thorough understanding of the molecular mechanisms underlying the disease are still lacking and incomplete. We dissect eutopic and ectopic...
ORGANISM(S): Homo sapiens (Human) 
2015-12-21 | PXD002845 | Pride
Stromal cell Proteomics Endometrium Silac Endometriosis Warburg effect 
TranscriptomicsTranscription profiling of human endothelial cells and pericytes from endometriotic nodules and control endometrial and myometrial tissue to identify specific markers of rectovaginal endometriotic nodule vasculature
To identify specific markers of rectovaginal endometriotic nodule vasculature, highly enriched preparations of vascular endothelial cells and pericytes were obtained from endometriotic nodules and control endometrial and myometrial tissue by laser capture microdissection (LCM), and gene expression p...
ORGANISM(S): Homo sapiens 
2007-09-30 | E-MEXP-1251 | biostudies-arrayexpress
ProteomicsCharacterization of stromal cells isolated from endometriotic lesions
Endometriosis shows significant lesion heterogeneity, but pathophysiological mechanisms leading to differences in clinical presentation are poorly understood. Here we utilized primary stromal cells from different types of endometriotic lesions to better understand the molecular mechanisms that lead ...
ORGANISM(S): Homo sapiens (Human) 
2025-12-15 | PXD066685 | Pride
Eutopic and ectopic endometrial cells Endometriosis Endometrioma Superficial endometriosis Endometrium Endometriotic stromal cells Homo sapiens Deep endometriosis 
TranscriptomicsCompulsory expression of miR-210 in normal endometrial stromal cells
Compulsory expression of miR-210 in normal endometrial stromal cells directed the induction of cell proliferation and vascular endothelial growth factor production, and the inhibition of apoptosis in through signal transducer and activator of transcription 3 (STAT3) activation. Accumulating evidence...
ORGANISM(S): Homo sapiens 
2015-04-06 | E-GEOD-56854 | biostudies-arrayexpress
GenomicsHOXC4 Promotes Proliferation of Endometriotic Stromal Cells via the SLIT2-ROBO1 Axis
HOXC4 Promotes Proliferation of Endometriotic Stromal Cells via the SLIT2-ROBO1 Axis
PRJNA1208666 | ENA
TranscriptomicsEndometriosis: Normal endometrial stromal cells and endometriotic stromal cells
Gene expression profiling of primary stromal cell cultures isolated from human endometrium and ovarian endometriosis. Samples are derived from the endometrium of 6 healthy patients and the endometriomas of 6 diseased patients. The results indicate the gene expression differences between these two ce...
ORGANISM(S): Homo sapiens 
2014-08-01 | E-GEOD-58178 | biostudies-arrayexpress
TranscriptomicsReciprocal communication between endometrial stromal cells and macrophages
Endometriosis is an inflammatory disease and bone marrow-derived cells are abundant in endometriotic lesions and in the peritoneal fluid of women with the disease. This study tested the hypothesis that reciprocal communication occurs between macrophages and cultured human endometrial stromal cells ...
ORGANISM(S): Homo sapiens 
2010-07-21 | E-GEOD-19834 | biostudies-arrayexpress
GenomicsEndometriotic Organoids: A Novel In Vitro Model of Endometriotic Lesion Development
Endometriotic Organoids: A Novel In Vitro Model of Endometriotic Lesion Development
PRJNA836898 | ENA
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