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ProteomicsAllele-specific alterations in the peptidome underlie the joint association of HLA-A*29:02 and Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) with Birdshot Chorioretinopathy
Birdshot chorioretinopathy (BSCR) is a rare inflammatory eye disease very strongly associated with HLA-A*29:02, with >95% of patients carrying this allele. BSCR is also associated with endoplasmic reticulum aminopeptidase (ERAP)2, an enzyme involved in processing HLA class I ligands. We analyzed the...
ORGANISM(S): Homo sapiens (Human) 
2018-05-17 | PXD007679 | Pride
Hla-a*29:02 Endoplasmic reticulum aminopeptidase 2 (erap2) Birdshot chorioretinopathy 
UnknownEvolutionary immuno-genetics of endoplasmic reticulum aminopeptidase II (ERAP2).
Not available
S-EPMC10721543 | biostudies-literature
UnknownModulation of Natural HLA-B*27:05 Ligandome by Ankylosing Spondylitis-associated Endoplasmic Reticulum Aminopeptidase 2 (ERAP2).
Not available
S-EPMC7261815 | biostudies-literature
UnknownAllele-specific Alterations in the Peptidome Underlie the Joint Association of HLA-A*29:02 and Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) with Birdshot Chorioretinopathy.
Not available
S-EPMC6072538 | biostudies-literature
UnknownTo Be or Not to Be: The Case of Endoplasmic Reticulum Aminopeptidase 2.
Not available
S-EPMC9234130 | biostudies-literature
UnknownDiscovery of Selective Inhibitors of Endoplasmic Reticulum Aminopeptidase 1.
Not available
S-EPMC8218592 | biostudies-literature
UnknownEndoplasmic Reticulum Aminopeptidase 2, a common immunological link to adverse pregnancy outcomes and cancer clearance?
Not available
S-EPMC5522626 | biostudies-literature
UnknownEndoplasmic Reticulum Associated Aminopeptidase 2 (ERAP2) Is Released in the Secretome of Activated MDMs and Reduces in vitro HIV-1 Infection.
Not available
S-EPMC6646713 | biostudies-literature
UnknownThe role of endoplasmic reticulum aminopeptidase 2 in modulating immune detection of choriocarcinoma.
Not available
S-EPMC5939618 | biostudies-literature
UnknownEndoplasmic reticulum aminopeptidase 2 regulates CD4+ T cells pyroptosis in rheumatoid arthritis.
Not available
S-EPMC10810225 | biostudies-literature
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