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ProteomicsKnockdown of endocytosis-related proteins in Trypanosoma brucei (TbVPS23)
TbVPS23 is part of the ESCRT-I (endosome-sorting complex required for transport-I) complex in Trypanosoma brucei. Moreover, TbTOM1 is an ortholog of human TOM1, which was identified in Trypanosomes by bioinformatic approaches, and is potentially implicated in endocytosis. We wanted to further invest...
ORGANISM(S): Trypanosoma brucei 
2026-08-24 | PXD060396 | Pride
Trypanosoma Tom1 Vps23 Gene silencing Endosome-sorting complex required for transport Endocytosis Rnai 
UnknownEvidence for a Golgi-to-endosome protein sorting pathway in Plasmodium falciparum.
Not available
S-EPMC3934947 | biostudies-literature
UnknownRetromer has a selective function in cargo sorting via endosome transport carriers.
Not available
S-EPMC6363445 | biostudies-literature
ProteomicsSNX3-retromer requires an evolutionary conserved MON2:DOPEY2:ATP9A complex to mediate Wntless sorting and Wnt secretion
Wntless transports Wnt morphogens to the cell surface and is required for Wnt secretion and morphogenic gradients formation. Recycling of endocytosed Wntless requires the sorting nexin-3 (SNX3)-retromer-dependent endosome-to-Golgi transport pathway. Here we demonstrate the essential role of SNX3-ret...
ORGANISM(S): Homo sapiens (Human) 
2018-10-16 | PXD010632 | Pride
Retromer flippase snx3 
UnknownBAG3 Regulation of RAB35 Mediates the Endosomal Sorting Complexes Required for Transport/Endolysosome Pathway and Tau Clearance.
Not available
S-EPMC9085972 | biostudies-literature
UnknownThe retromer coat complex coordinates endosomal sorting and dynein-mediated transport, with carrier recognition by the trans-Golgi network.
Not available
S-EPMC2714578 | biostudies-literature
UnknownIk2/TBK1 and Hook/Dynein, an adaptor complex for early endosome transport, are genetic modifiers of FTD-associated mutant CHMP2B toxicity in Drosophila.
Not available
S-EPMC7450086 | biostudies-literature
UnknownFAM21 directs SNX27-retromer cargoes to the plasma membrane by preventing transport to the Golgi apparatus.
Not available
S-EPMC4786876 | biostudies-literature
UnknownA conserved late endosome-targeting signal required for Doa4 deubiquitylating enzyme function.
Not available
S-EPMC2064681 | biostudies-literature
UnknownESCRT-0 is not required for ectopic Notch activation and tumor suppression in Drosophila.
Not available
S-EPMC3981749 | biostudies-literature
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