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TranscriptomicsTranscription profiling of human samples after exercise training to characterize a colony assay used to investigate endothelial progenitor cells
Subjects underwent endothelial testing and blood sampling at baseline and after 3 months of exercise training. Microarray and flow cytometry-based characterization of cells from an endothelial progeniator colony assay was consistent with T lymphocytes, but not endothelial cells. Experiment Overall ...
ORGANISM(S): Homo sapiens 
2009-01-13 | E-GEOD-12155 | biostudies-arrayexpress
TranscriptomicsHuman umbilical cord blood-derived endothelial colony forming cells under serum-free conditions
Derivation and expansion of human umbilical cord blood-derived endothelial colony forming cells under serum-free conditions - a transcriptome analysis. Endothelial colony forming cells (ECFCs) were isolated from term umbilical cord blood units. ECFCs were expanded under standard, fetal bovine serum ...
ORGANISM(S): Homo sapiens 
2010-07-29 | E-GEOD-20504 | biostudies-arrayexpress
GenomicsGenomic binding profile of TAL1 in human Endothelial Colony-Forming Cells
Endothelial colony-forming cells (ECFCs) have been reported as promising cells for regenerative medicine thanks to their angiorepair properties. Transcription factors are primary determinants of the functional capacity of the cells and TAL1 has been shown as a critical regulator of endothelial linea...
ORGANISM(S): Homo sapiens 
2014-05-06 | E-GEOD-44442 | biostudies-arrayexpress
GenomicsKSHV infection of Endothelial Colony Forming Cells
KSHV infection of Endothelial Colony Forming Cells
PRJNA856285 | ENA
TranscriptomicsshRNA mediated knock-down of Tal1 in human Endothelial Colony Forming Cells (ECFCs)
Endothelial colony-forming cells (ECFCs) have been reported as promising cells for regenerative medicine thanks to their angiorepair properties. Transcription factors are primary determinants of the functional capacity of the cells and TAL1 has been shown as a critical regulator of endothelial linea...
ORGANISM(S): Homo sapiens 
2014-05-06 | E-GEOD-44444 | biostudies-arrayexpress
TranscriptomicsProspective surface marker-based isolation and expansion of fetal endothelial colony-forming cells from human term placenta.
The term placenta is a highly vascularized tissue and is usually discarded upon birth. Our objective was to isolate clinically relevant quantities of fetal endothelial colony-forming cells (ECFCs) from human term placenta and to compare them to the well-established donor-matched umbilical cord blood...
ORGANISM(S): Homo sapiens 
2015-03-02 | E-MTAB-3277 | biostudies-arrayexpress
ProteomicsDistinct phenotype and proteomic signature of peripheral blood-endothelial colony-forming cells of subjects with varied cardiovascular disease risks
Endothelial progenitor cells (EPCs) are circulating endothelial precursors shown to incorporate into foci of neovascularisation. Herein, we describe phenotypic characteristics of an EPC sub-type called endothelial colony-forming cells (ECFCs). Peripheral blood-isolated ECFCs expressed endothelial an...
ORGANISM(S): Homo sapiens (Human) 
2022-02-15 | PXD020677 | Pride
Cardiovascular disease Endothelial progenitor cells 
TranscriptomicsDerivation of endothelial colony forming cells from human pluripotent stem cells
Human induced pluripotent stem (hiPS) cells and human embryonic stem (hES) cells differentiate into cells of the endothelial lineage, but derivation of cells with human umbilical cord blood endothelial colony forming cell (ECFC)-like properties has not been reported. Here we describe a novel serum- ...
ORGANISM(S): Homo sapiens 
2014-07-18 | E-GEOD-49074 | biostudies-arrayexpress
ProteomicsEndothelial Colony Forming Cells Characteristics in a healthy and VWD patient cohort.
Background Endothelial cells are crucial for hemostasis as they produce Von Willebrand factor (VWF). Von Willebrand Disease (VWD) results from a deficiency or defects in VWF, However, diagnosis is difficult due to large differences between gene variants and bleeding phenotype. Here, we analyze the e...
ORGANISM(S): Homo sapiens (Human) 
2024-11-28 | PXD055124 | Pride
Proteomics Endothelial cell Ecfc Vwd 
TranscriptomicsEffects of co-culture of Endothelial Cells with Mesenchymal Stem Cells on Gene Expression
Study designed to explore the effects of endothelial cell/MSC co-culture on individual gene expression profile of each cell type 4 independent samples from each of 4 groups: MSCs cultured alone; Pulmonary endothelial cells cultured alone; MSCs co-cultured with PECs then FACS separated; PECs co-cultu...
ORGANISM(S): Homo sapiens 
2012-09-15 | E-GEOD-40613 | biostudies-arrayexpress
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