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Single cell RNA-seq analysis of endothelial cells (HUVEC) treated with IL1b and TGFb2 as a model of endothelial to mesenchymal transition (EndMT)
Background: Following myocardial infarction, mitral regurgitation (MR) is a common complication. Previous animal studies demonstrated the association of endothelial-to-mesenchymal transition (EndMT) with mitral valve (MV) remodeling. Nevertheless, little is known about how MV tissue responds to isch...
ORGANISM(S): Homo sapiens (Human) 
2021-08-13 | PXD025096 | Pride
The tumor microenvironment (TME) of non-small cell lung cancer (NSCLC) is highly heterogeneous and is involved in tumorigenesis and resistance to therapy. Among the cells of the TME, endothelial cells are associated with the latter processes through endothelial-to-mesenchymal transition (EndMT). Dur...
ORGANISM(S): Homo sapiens (Human) 
2025-04-24 | PXD054295 | Pride
LARP7 suppresses endothelial-to-mesenchymal transition by coupling with TRIM28
Transcriptome changes during Endothelial to Mesenchymal Transition (EndMT) using a TGF-b2 and IL-1b in vitro model of EndMT in HUVEC and HPAEC
The histone demethylase JMJD2B regulates endothelial-to-mesenchymal transition [microarray]
The histone demethylase JMJD2B regulates endothelial-to-mesenchymal transition [HTS]
Long non-coding RNA MIR503HG controls endothelial-to-mesenchymal transition
Endothelial-to-mesenchymal transition (EndMT) is a dynamic biological process involved in pathological vascular remodeling. However, the molecular mechanisms that govern this transition remain largely unknown. To study EndMT in vitro, human umbilical vein endothelial cells (HUVEC) were treated with ...
ORGANISM(S): Homo sapiens 
2021-04-06 | GSE159843 | GEO
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