Engineered cardiac tissue

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Mass Spectrometry (16)
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CHEBI ID

CHEBI:16750 (2)
CHEBI:16015 (2)
CHEBI:32816 (2)
CHEBI:30887 (2)
CHEBI:30915 (2)
CHEBI:30769 (2)
CHEBI:57608 (1)
CHEBI:48042 (1)
CHEBI:132941 (1)
CHEBI:20506 (1)
CHEBI:55404 (1)
CHEBI:37736 (1)
CHEBI:18105 (1)
CHEBI:57737 (1)
CHEBI:21519 (1)
CHEBI:35425 (1)
CHEBI:22651 (1)
CHEBI:139582 (1)
CHEBI:62168 (1)
CHEBI:51340 (1)
CHEBI:17973 (1)
CHEBI:15633 (1)
CHEBI:17797 (1)
CHEBI:15954 (1)
CHEBI:17983 (1)
CHEBI:15820 (1)
CHEBI:35374 (1)
CHEBI:17925 (1)
CHEBI:16082 (1)
CHEBI:15811 (1)

Metabolite Name

C00049 (1)
1,4-Dihydronicotinamide adenine dinucleotide (NADH) (1)
5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate (1)
Pristanic acid (1)
Acetyl phosphate (1)
N-acetyl-DL-methionine (1)
N-acetyl-D-tryptophan (1)
Aminovaleric acid betaine (1)
4-hydroxystradiol (1)
HMDB0000511 (1)
Cis-aconitic acid (1)
D-ribose 5-phosphate (1)
1-aminocyclopropane-1-carboxylate (1)
1-Carboxyethylleucine (1)
Alpha-D-glucose (1)
O-butanoyl-L-carnitine (1)
O-phospho-L-serine (1)
Glutarate (1)
5-oxo-L-proline (1)
11Z-Octadecenylcarnitine (1)
25,26-dihydroxyvitamin D (1)
2-Hydroxyhexadecanoylcarnitine (1)
Docosapentaenoic acid (22n-6) (1)
O-isobutyryl-L-carnitine (1)
Hepoxilin A3 (1)
Docosapentaenoic acid (22n-3) (1)
L-cystathionine (1)
Alpha-ketoglutaric acid (1)
21-Deoxycortisol (1)
O-acetyl-L-carnitine (1)

First Public Date

2026 (15)
2024 (11)
2025 (10)
2023 (7)
2020 (7)
2022 (5)
2014 (4)
2021 (2)
2019 (2)
2017 (1)
2015 (1)

Study type

Transcription profiling by array (25)
Unknown experiment type (5)
RNA-seq of coding RNA (4)
RNA-seq of coding RNA from single cells (3)
RNAi profiling by array (1)
Transcription profiling by RT-PCR (1)
Comparative genomic hybridization by array (1)
Other (1)
DNA-seq (1)

Release Date

2023 (52)
2020 (51)
2021 (46)
2025 (44)
2019 (43)
2022 (40)
2018 (35)
2016 (30)
2024 (28)
2015 (23)
2014 (22)
2017 (22)
2026 (15)
2013 (14)
2012 (11)
2011 (10)
2010 (10)
2009 (6)
2008 (3)
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2001 (1)

Lab affiliation

Executive Science Officer, BioFrontiers InstituteDistinguished ProfessorProfessor, Howard Hughes Medical Institute MOLECULAR CELLULAR AND DEVELOPMENTAL BIOLOGY CU DENVER SCHOOL OF MEDICINE (2)
Department of Biotechnology, Yonsei University, Republic of Korea (1)
Department of Experimental Pharmacology and 35 Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, 36 Martinistrasse 52, 20246 Hamburg, Germany (1)
University of Chieti-Pescara, Depatment of Pharmacy (1)
Laboratory for Functional Genome Analysis Genzentrum Ludwig-Maximilians-Universität München Feodor-Lynen-Str. 25 D-81377 München Germany (1)
School of Biomedical Sciences, The University of Queensland, St Lucia 4072, Queensland, Australia. (1)
Chief Scientific Officer, BioFrontiers Institute Distinguished Professor, Department of Molecular, Cellular, and Developmental Biology Professor, Howard Hughes Medical Institute (1)
Toronto General Hospital Research Institute, University Health Network; Toronto, Ontario, Canada; Temerty Faculty of Medicine, University of Toronto; Toronto, Ontario, Canada; Peter Munk Cardiac Centre, University Health Network; Toronto, Ontario, Canada. (1)
Department of Immunology, University of Toronto, Canada Toronto General Hosptial Research Institute, University Health Network, Canada (1)
Department of Immunology, University of Toronto, Canada Toronto General Hospital Research Institute, University Health Network, Canada (1)
Institute of Pharmacology & Toxicology, University Medical Center Göttingen, Germany. Medical Clinic I, Department of Cardiology and Angiology, Justus Liebig University, Giessen, Germany. German Centre for Cardiovascular Research (DZHK e.V.), partner sites Lower Saxony, Heidelberg/Mannheim, Munich, Hamburg/Kiel/Lübeck, RhineMain, Germany. Cardio-Pulmonary Institute (CPI), Giessen, Germany. (1)
Baker Heart & Diabetes Inst. (1)
CNIC (1)
King’s British Heart Foundation Centre of Research Excellence, King's College London, United Kingdom (1)
University of Wisconsin-Madison (1)

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Cross-modal Integration of Metabolomics and Cardiac Functionality Captures Dynamic Metabotoxic Effects of Doxorubicin in Engineered Heart Tissues

Functional stem cell-derived heart models offer new avenues for preclinical, animal-free physiological assessment of drug cardiotoxicity. Yet, comprehensive molecular profiling in these models remains limited, leaving key metabolic drivers of cardiotoxicity unexplored.

Here, we leveraged an...

2025-12-07 | MTBLS13225 | MetaboLights

Lactate and Immunomagnetic-purified iPSC-derived Cardiomyocytes Generate Comparable Engineered Cardiac Tissue Constructs

top down and bottom up proteomics files for Lactate and Immunomagnetic-purified iPSC-derived Cardiomyocytes Generate Comparable Engineered Cardiac Tissue Constructs

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2023-05-05 | MSV000091869 | MassIVE

Engineered Oncolytic VSV Enhances Tumor Killing in HBV-Positive HCC

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide, with chronic hepatitis B virus (HBV) infection being a major contributor to its development. Despite this, effective treatment for HBV-associated HCC remains a significant challenge. In this study, we combined the s...

2025-07-17 | MTBLS12196 | MetaboLights

Fibrin and GelMA hydrogel MEW-based human engineered cardiac tissue

PRJNA1400027 | ENA

Transcriptomic analysis of engineered cardiac tissue in an oxygen gradient

PRJNA781583 | ENA

hiPSC-derived CF proportions in MEW-based human engineered cardiac tissue

PRJNA1400025 | ENA

Macrophages enhance contractile force in iPSC-derived human engineered cardiac tissue

PRJNA1108328 | ENA

Phenotypic variation between stromal cells differentially impacts engineered cardiac tissue function

PRJNA529887 | ENA

Cardiac conduction through engineered tissue.

Not available

S-EPMC1534117 | biostudies-literature

Functionally Integrated Top-down Proteomics for Standardized Assessment of Human Induced Pluripotent Stem Cell-derived Engineered Cardiac Tissues

3-dimensional (3D) human induced pluripotent stem cell-derived engineered cardiac tissues (hiPSC-ECTs) have emerged as a promising alternative to 2-dimensional hiPSC-cardiomyocyte monolayer systems because hiPSC-ECTs are a closer representation of endogenous cardiac tissues and more faithfully refle...

ORGANISM(S): Homo sapiens (Human)

2021-01-07 | PXD022814 | Pride

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