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GenomicsTransplantation-induced reprogramming determines successful hepatocyte engraftment
Transplantation-induced reprogramming determines successful hepatocyte engraftment
PRJNA1150161 | ENA
GenomicsTransplantation-induced progenitor-like state determines successful hepatocyte engraftment
Transplantation-induced progenitor-like state determines successful hepatocyte engraftment
PRJNA1149797 | ENA
TranscriptomicsPRC2 inhibition counteracts the culture-associated loss of engraftment potential of human cord blood-derived hematopoietic stem and progenitor cells
Cord blood hematopoietic stem cells (CB-HSCs) are an outstanding source for transplantation approaches. However, the amount of cells per donor is limited and culture expansion of CB-HSCs is accompanied by a loss of engraftment potential. In order to analyze the molecular mechanisms leading to this i...
ORGANISM(S): Homo sapiens 
2015-08-07 | E-GEOD-58461 | biostudies-arrayexpress
MetabolomicsDonor Gut MicrobialDrives Fecal Microbiota Transplantation Efficacy in ulcerative colitis

Fecal microbiota transplantation (FMT) has emerged as a promising therapeutic strategy for Inflammatory Bowel Disease (UC), though its clinical success appears contingent upon donor microbiota engraftment degree. While microbial colonization dynamics remain poorly understood, our study identifies...

2026-01-11 | MTBLS12531 | MetaboLights
ProteomicsMolecular correlates of HNSCC engraftment
We performed proteomic profiling of 88 HNSCC patients to investigate the molecular phenotype associated with engraftment. We complemented the analysis with HNSC and normal oral epithelial cell lines.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-04-09 | MSV000094507 | MassIVE
GenomicsZebrafish chemical compound screen uncovers inducers of skeletal muscle engraftment across species
Zebrafish chemical compound screen uncovers inducers of skeletal muscle engraftment across species
PRJNA601746 | ENA
GenomicsTranscriptome data from human endocrine cells recovered from mouse grafts with pre-engraftment controls
Transcriptome data from human endocrine cells recovered from mouse grafts with pre-engraftment controls
PRJNA577039 | ENA
TranscriptomicsDissecting engineered cell types and enhancing cell fate conversion via CellNet
Engineering clinically relevant cells in vitro holds promise for regenerative medicine, but most protocols fail to faithfully recapitulate target cell properties. To address this, we developed CellNet, a network biology platform that determines whether engineered cells are equivalent to their target...
ORGANISM(S): Mus musculus 
2014-08-14 | E-GEOD-59037 | biostudies-arrayexpress
GenomicsMolecular correlates for HPV-negative head and neck cancer engraftment prognosticate patient outcomes
Molecular correlates for HPV-negative head and neck cancer engraftment prognosticate patient outcomes
PRJNA1173116 | ENA
TranscriptomicsTransplantation-induced reprogramming determines successful hepatocyte engraftment
While demonstrated safety and efficacy in treating liver diseases, hepatocyte-based therapy faces the challenge of limited engraftment of transplanted hepatocytes (Tx-Heps) in clinical settings, akin to issues encountered in cell therapy for other solid organs. Here, we identified a conserved reprog...
ORGANISM(S): Mus musculus Homo sapiens 
2025-08-18 | GSE275278 | GEO
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