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Targeted proteomics has been playing an increasingly important role in hypothesis-driven protein research and clinical bi-omarker discovery. We have previously created a workflow, Tomahto, to enable real-time targeted pathway proteomics assays using two-dimensional multiplexing technology. Coupled w...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-08-14 | MSV000095604 | MassIVE
The yeast, Saccharomyces cerevisiae, is a widely used model system for investigating conserved biological functions and pathways. Advancements in sample multiplexing have facilitated the study of the yeast proteome, yet many yeast proteins remain uncharacterized or only partially characterized. The ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-09-02 | PXD032042 | Pride
Targeted proteomics plays a specialized role in hypothesis-driven research where the expression of cohorts of dozens of proteins related by function, disease, co-expression, localization, or class are measured after perturbing a pathway. Moreover, a major advance in proteomics is the ability to comb...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD029461 | Pride
These datasets are test datasets of sample-multiplexed scRNA-seq, consisting of cDNA (transcriptome) and sample barcode read files: Three-sample multiplexing experiment (JS009) is a MULTI-seq dataset containing mesenchyme embryonic hind limb bud cells, embryonic stem (ES) cells, and NIH3T3 cells. Ea...
ORGANISM(S): Mus musculus 
Impact of sample multiplexing on detection of bacteria and antimicrobial resistance genes in pig microbiomes using long-read sequencing
The GET pathway is associated with post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum (ER) in yeast, as well as other eukaryotes. Moreover, dysfunction of the GET pathway has been associated with various pathological conditions. In this study, we used yeast delet...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-12-28 | PXD044391 | Pride
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