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MetabolomicsGiardiavirus infection mediates Enolase to the upregulation of Glycolysis in Giardia

Giardia duodenalis is a prevalent intestinal parasite that cause giardiasis, a condition characterized by diarrhea and frequently linked to malnutrition and growth impairments in children. The presence of Giardiavirus (GLV) can lead to reduced pathological damage in mice infected with Giardia and...

2025-07-05 | MTBLS12615 | MetaboLights
TranscriptomicsTranscription profiling by array of human HT29 colon cancer cells to investigate the role of Caveolin 1, E-Cadherin, Enolase 2 and PKCa on resistance to methotrexate
A summary of the work associated to these microarrays is the following:; Methotrexate (MTX) is one of the earliest cytotoxic drugs used in cancer therapy, and despite the isolation of multiple other folate antagonists, methotrexate maintains its significant role as a treatment for different types of...
ORGANISM(S): Homo sapiens 
2008-10-25 | E-GEOD-11440 | biostudies-arrayexpress
ProteomicsAMOXICILLIN HAPTENATION OF α-ENOLASE
Allergic reactions to antibiotics are a major concern in the clinic, with almost 15% of the patients presenting with adverse reactions against β-lactam antibiotics. One of the mechanisms involved in this outcome is the modification of proteins by covalent binding of the drug (haptenation). Hence, th...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD029712 | Pride
Β-lactam antibiotics  protein modification by drugs  mass spectrometry  posttranslational modifications  acetylation  allergic responses to drugs 
ProteomicsDetection of Acetylated Neuron Specific Enolase gamma
Immunoaffiniyt purification followed by intact-mass detection of the acetylated lung tumor biomarker Neuron Specific Enolase.
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD053170 | Pride
Acetylation Top-down Ptm Neuron specific enolase 
TranscriptomicsENOLASE treated PBMC vs Control relative to time
Time dependant transcriptional profiling of healthy PBMC comparing a-ENOLASE (ENO) treatment to BSA (Control). Kinetic was performed : H0, H5, H20 and H45. Goal was to determine the biological pathways relative to ENO treatment.
ORGANISM(S): Homo sapiens 
2016-06-01 | GSE68089 | GEO
ProteomicsLiving cell surface proteome - Tracing putative trafficking of the glycolytic enzyme enolase via SNARE-driven unconventional secretion
Living cell surface proteome - Tracing putative trafficking of the glycolytic enzyme enolase via SNARE-driven unconventional secretion
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2012-07-20 | PRD000729 | Pride
TranscriptomicsENOLASE treated PBMC vs Control relative to time
Time dependant transcriptional profiling of healthy PBMC comparing a-ENOLASE (ENO) treatment to BSA (Control). Kinetic was performed : H0, H5, H20 and H45. Goal was to determine the biological pathways relative to ENO treatment. Two-condition experiment, ENO vs. Control - PBMC. Biological replicates...
ORGANISM(S): Homo sapiens 
2016-06-01 | E-GEOD-68089 | biostudies-arrayexpress
MetabolomicsMetabolite profiling of Arabidopsis mutants of enzymes of lower glycolysis
We have previously shown that in Arabidopsis the three enzymes of lower glycolysis phosphoglycerate mutase (PGAM), enolase and pyruvate kinase form a complex which play an important role in co-sub-cellar localization the mitochondria to the chloroplast. Given that their metabolites of these mutants,...
2022-10-10 | MTBLS4066 | MetaboLights
UnknownPlasmodium falciparum enolase complements yeast enolase functions and associates with the parasite food vacuole.
Not available
S-EPMC3353271 | biostudies-literature
UnknownCrystal structure of enolase from Drosophila melanogaster.
Not available
S-EPMC5379173 | biostudies-literature
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