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GenomicsGenome-wide eNOS-DNA association in Prostate Cancer Cells
ChIP-Sequencing using antibody to eNOS in cells from a primary prostate cancer with poor outcome and metastatic LNCaP cells, in basal condition and after E2 treatment
ORGANISM(S): Homo sapiens 
2013-11-04 | E-MTAB-1204 | biostudies-arrayexpress
ProteomicseNOS interactors in human cells
Endothelial nitric oxide synthase (eNOS) catalyzes the conversion of L-arginine and molecular oxygen into L-citrulline and nitric oxide (NO), a gaseous second messenger that influences cardiovascular physiology and disease. Several mechanisms regulate eNOS activity and function, including phosphoryl...
ORGANISM(S): Homo sapiens (Human) 
2018-10-24 | PXD002598 | Pride
Enos Stromal cell-derived factor 2 
TranscriptomicsTranscription profiling of mouse left ventricle from male (-/-) (n=3) and (+/+) (n=4) at the age of 21M to do exercise and transcriptional analysis in male eNOS Knockout Mice
There is cardiac dysfunction in male eNOS (-/-) with age and 50% mortality at 21M. It was of interest to investigate the gene expression profile of aged eNOS (-/-) male in comparison to (+/+) in order to explore the genetic markers and molecular mechanisms leading to heart failure. RNA was extracted...
ORGANISM(S): Mus musculus 
2007-11-06 | E-GEOD-1988 | biostudies-arrayexpress
TranscriptomicsComparison of Glomerular and Podocyte mRNA Profiles in eNOS-/- Diabetic Mice Induced by Streptozotocin
We compared mRNA profiles of isolated glomeruli versus sorted podocytes between diabetic and control mice. IRG mice crossed with eNOS-/- mice were further bred with podocin-rTTA and TetON-Cre mice to permanently label podocytes before the diabetic injury. Diabetes was induced by injection of strepto...
ORGANISM(S): Mus musculus 
2016-03-16 | E-GEOD-79291 | biostudies-arrayexpress
TranscriptomicsSlit2 modifies VEGF-induced angiogenic responses in rabbit skeletal muscle by inducing capillary sprouting and decreasing vascular permeability via reduced eNOS activity
Rationale: Slit2 is a possible modulator of vascular endothelial growth factor (VEGF) - induced angiogenesis, but its effects have not been tested in large animal models. Objective: We studied the effect of Slit2 on therapeutic angiogenesis induced by VEGF receptor 2 (VEGFR2) ligands Vammin and VEGF...
ORGANISM(S): Homo sapiens 
2015-05-26 | E-GEOD-63283 | biostudies-arrayexpress
GenomicsGene expression for eNOS S1176 mutant mice
Gene expression for eNOS S1176 mutant mice
PRJNA1015707 | ENA
ProteomicsProteomic analysis of the liver isolated from the double (apolipoprotein E and endothelial nitric oxide synthase) knockout mice reveals decreased expression of major urinary proteins (MUPs)
Nitric oxide (NO) is a crucial gaseous signaling molecule engaged in a variety of physiological and pathological processes. It is produced by three isoenzymes called nitric oxide synthases (NOS): neuronal, inducible and endothelial NOS (eNOS). eNOS-derived NO plays an important role in endothelium-d...
ORGANISM(S): Mus musculus (Mouse) 
2018-03-05 | PXD006642 | Pride
Proteomics Liver Mup Apolipoprotein e Enos 
GenomicsTranscriptional profiling identifies white matter changes in eNOS+/- mice II
Transcriptional profiling identifies white matter changes in eNOS+/- mice II
PRJNA857744 | ENA
GenomicsTranscriptional profiling identifies white matter changes in eNOS+/- mice I
Transcriptional profiling identifies white matter changes in eNOS+/- mice I
PRJNA857743 | ENA
GenomicsGenome-wide eNOS-DNA association in Prostate Cancer Cells
Genome-wide eNOS-DNA association in Prostate Cancer Cells
PRJEB3188 | ENA
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