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MetabolomicsExposure to environmental hazard pesticide rotenone triggers redox driven system-wide lipidome alterations and metabolic trade-offs linked to Parkinson’s disease

With the global rise in aging populations, the increasing incidence of neurodegenerative diseases underscores concerns about brain health, with pesticides like rotenone, emerging as key environmental hazardous. The precise mechanism by which chronic environmental concentration of rotenone exposur...

2025-01-28 | MTBLS11699 | MetaboLights
MetabolomicsIntegrated Exposomics/Metabolomics for Rapid Exposure and Effect Analyses

The totality of environmental exposures and lifestyle factors, commonly referred to as the exposome, are poorly understood. Measuring the myriad of chemicals that humans are exposed to is immensely challenging and identifying disrupted metabolic pathways is even more complex. Here, we present a n...

2023-10-26 | MTBLS4556 | MetaboLights
MetabolomicsIntegrated analysis of faecal microbial diversity and serum metabolome reveals the profiling of gut microbiota-related metabolites in rats and mice prolonged exposure to environmental high humidity

Background: High humidity, as a key climate risk factor, has become one of the significant threats to public health. However, less is known about the mechanism by which the high humidity environment affects the health of the population. The present study was designed to reveal the profile of gut ...

2026-06-16 | MTBLS5660 | MetaboLights
MetabolomicsExposure to known and emerging groundwater contaminants significantly alters poultry microbiome and metabolome

The exposome represents a summation of exposures which influence an individual’s health over their lifetime. Understanding the exposome will aid in determining the environmental factors that contribute to disease states. Due to the biological complexity of the exposome and the resulting high dime...

2025-07-04 | MTBLS11958 | MetaboLights
MetabolomicsMetabolomic profiling of goat testicular tissue under graded uranium exposure

This study presents metabolomic profiles of goat testicular tissue obtained under controlled exposure conditions. An untargeted metabolomics approach was applied to characterize global metabolic alterations associated with environmental contaminants. The dataset provides information on small-mole...

2026-03-23 | MTBLS14119 | MetaboLights
MetabolomicsIntegrated analysis of faecal microbial diversity and serum metabolome reveals the profiling of gut microbiota-related metabolites in rats and mice prolonged exposure to environmental high humidity

Background: High humidity, as a key climate risk factor, has become one of the significant threats to public health. However, less is known about the mechanism by which the high humidity environment affects the health of the population. The present study was designed to reveal the profile of gut ...

2026-06-16 | MTBLS5653 | MetaboLights
MetabolomicsEnterococcus faecalis readily adapts membrane phospholipid composition to environmental and genetic perturbation

The bacterial lipid membrane, consisting both of fatty acid (acyl) tails and polar head groups, responds to changing conditions through alteration of either the acyl tails and/or head groups. This plasticity is critical for cell survival as it allows maintenance of both the protective nature of t...

2021-05-17 | MTBLS2080 | MetaboLights
ProteomicsEnvironmental Pollutant Induced Cellular Injury is Reflected in Exosomes from Placental Explants
Environmental exposure of placental explants did not change the quantity of exosomes or their characteristics. However, exosome cargo composition was changed by specific pollutant to reflect a biochemical signature suggestive of placental nuclear and cellular injury and inflammation.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000084274 | MassIVE
MetabolomicsThe impact of tobacco smoke exposure and environmental exposures on the pulmonary microbiome of critically ill children
Not available
ORGANISM(S): Homo sapiens 
ST001262 | MetabolomicsWorkbench
MetabolomicsEnvironmental Chemical Diethylhexyl Phthalate Alters Intestinal Microbiota Community Structure and Metabolite Profile in Mice
Exposure to environmental chemicals during windows of development is a potentially contributing factor in gut microbiota dysbiosis, and linked to chronic diseases and developmental disorders. We used a community-level model of microbiota metabolism to investigate the effects of diethylhexyl phthalat...
2022-01-17 | MTBLS861 | MetaboLights
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