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Eosinophilic oesophagitis (EoE) is a leading cause of dysphagia and food impaction in children and adults. In this pilot study, we performed genome-wide DNA methylation analyses on oesophageal biopsies obtained from children diagnosed with EoE (at diagnosis and after treatment) and matched controls....
ORGANISM(S): Homo sapiens 
We utilized RNA sequencing to expand and better define the molecular entities involved in the transcriptional programming within the eosphagus in eosinophilic esophagitis (EoE) Examination of differentially expressed genes from RNA sequencing data performed on esophageal biopsy specimen from 6 healt...
ORGANISM(S): Homo sapiens 
Genotyping of EoE Subjects
Genotyping of EoE Subjects
The EoE esophageal epithelial transcriptomic landscape
Eosinophlic esophagitis (EoE) is increasely recognized as an antigen-drived disorder. The goal of this study is to reveal the miRNA expression changes in EoE before and after a successful glucocorticoid steroid treatment. Total RNA was extracted from the esophageal epithelial layers of 5 paired para...
ORGANISM(S): Homo sapiens 
characterize inflammatory proteins enriched in IgG4+ lesions in human esophageal tissues
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD037663 | Pride
To test the ability of the Automated Spatially Targeted Optical Micro Proteomics (AutoSTOMP) protocol for clinical research. We collected from a patient diagnosed with active EoE (≥15 eosinophils/hpf), according to consensus guidelines, using standard endoscopy procedures, then we try to selectively...
ORGANISM(S): Homo sapiens (Human) 
2021-08-10 | PXD026819 | Pride
Characteristics and inflammatory markers in children with Eosinophilic Esophagitis (EoE)
Characteristics and inflammatory markers in children with Eosinophilic Esophagitis (EoE)
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