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ProteomicsGenetic profiling and surface proteome analysis of epicardial derived cells reveals cardiogenic potential
Rationale: Epicardium-derived cells (EPDC) are formed in response to myocardial infarction and recapitulate an embryonic program that is likely to participate in cardiac regeneration and remodeling. The existence of atrial counterparts that are potentially involved in atrial remodeling is still elus...
ORGANISM(S): Homo sapiens (Human) Rattus norvegicus (Rat) 
2018-10-19 | PXD005013 | Pride
Stem cell Surface proteome Epdc 
UnknownSingle-cell analysis reveals an Angpt4-initiated EPDC-EC-CM cellular coordination cascade during heart regeneration.
Not available
S-EPMC10166170 | biostudies-literature
UnknownEpicardial Outgrowth Culture Assay and Ex Vivo Assessment of Epicardial-derived Cell Migration.
Not available
S-EPMC4829037 | biostudies-literature
TranscriptomicsComparison of gene expression data between control and tissue specific epicardial PDGF receptor (a and b) knockout embryonic hearts
Epicardial cells undergo an epithelial-to-mesenchymal transtion (EMT) to generate coronary vascular smooth muscle cells (VSMC) and cardiac fibroblasts. Little is known about the mechanisms regulating EMT or the in vivo signals directing epicardial-derived cell (EPDC) fate. Here, we show that loss of...
ORGANISM(S): Mus musculus 
2011-02-28 | GSE27181 | GEO
TranscriptomicsComparison of gene expression data between control and tissue specific epicardial PDGF receptor (a and b) knockout embryonic hearts
Epicardial cells undergo an epithelial-to-mesenchymal transtion (EMT) to generate coronary vascular smooth muscle cells (VSMC) and cardiac fibroblasts. Little is known about the mechanisms regulating EMT or the in vivo signals directing epicardial-derived cell (EPDC) fate. Here, we show that loss ...
ORGANISM(S): Mus musculus 
2011-02-28 | E-GEOD-27181 | biostudies-arrayexpress
UnknownMyocardin-related transcription factors control the motility of epicardium-derived cells and the maturation of coronary vessels.
Not available
S-EPMC4299137 | biostudies-literature
UnknownCTGF-D4 Amplifies LRP6 Signaling to Promote Grafts of Adult Epicardial-derived Cells That Improve Cardiac Function After Myocardial Infarction.
Not available
S-EPMC9199845 | biostudies-literature
UnknownEvaluating a Model to Predict Primary Care Physician-Defined Complexity in a Large Academic Primary Care Practice-Based Research Network.
Not available
S-EPMC4636571 | biostudies-literature
TranscriptomicsLMNA-Related Dilated Cardiomyopathy: Single-Cell Transcriptomics during Patient-Derived iPSC Differentiation Support Cell Type and Lineage-Specific Dysregulation of Gene Expression and Development for Cardiomyocytes and Epicardium-Derived Cells
LMNA-Related DCM involves cardiomyocyte dysfunction resulting in heart failure or sudden death. It is caused by LMNA mutations encoding Lamin A/C defects involved in nuclear integrity and gene expression. To investigate possible mechanisms, we used iPSC derived from a LMNA c.357-2A>G Patient and her...
ORGANISM(S): Homo sapiens 
2024-09-03 | GSE269705 | GEO
TranscriptomicsA miR-200b-Filamin A axis drives epicardial contribution to cardiogenesis
The epicardium provides essential cellular and molecular cues required for proper cardiogenesis and cardiac repair. Epicardial-derived cells (EPDCs) play a pivotal role in establishing cardiac structure, contributing to coronary vasculature formation, connective tissue organization, and post-ischemi...
ORGANISM(S): Mus musculus 
2025-11-29 | GSE311233 | GEO
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