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ProteomicsGenetically Variant Peptide Biomarkers from Fingermarks
This dataset results from the discovery, characterization and validation of 74 genetically variant peptides from fingermark protein. These peptides contain single amino acid polymorphisms, the result of non-synonymous SNPs. Detection of these peptide markers in fingermark proteomic datasets allows i...
ORGANISM(S): Homo sapiens (Human) 
2019-06-19 | PXD012628 | Pride
Fingermarks Genetically variant peptides Forensic science Proteomics Epidermal corneocytes 
UnknownProtein profiling of forehead epidermal corneocytes distinguishes frontal fibrosing from androgenetic alopecia.
Not available
S-EPMC10065298 | biostudies-literature
TranscriptomicsBroad defects in epidermal cornification in atopic dermatitis (AD) identified through genomic analysis
In this study we used genomic profiling to characterize differences in expression of genes related to epidermal growth/differentiation and inflammatory circuits in skin lesions of psoriasis and atopic dermatitis (AD), comparing expression values to normal skin. Skin biopsies were collected from 9 pa...
ORGANISM(S): Homo sapiens 
2009-10-31 | E-GEOD-16161 | biostudies-arrayexpress
ProteomicsProtein Profiling of Forehead and Scalp Corneocytes in Androgenetic versus Frontal Fibrosing Alopecia
Protein profiling offers an effective approach to characterizing the departure from normal of epidermis in disease states. The present investigation tested the hypothesis that the differentiation of epidermal corneocytes is perturbed in the forehead of subjects exhibiting frontal fibrosing alopecia....
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-08-16 | MSV000090141 | MassIVE
UnknownInactivation of DNase1L2 and DNase2 in keratinocytes suppresses DNA degradation during epidermal cornification and results in constitutive parakeratosis.
Not available
S-EPMC5527052 | biostudies-literature
UnknownComparative genomics of monotremes provides insights into the early evolution of mammalian epidermal differentiation genes.
Not available
S-EPMC10791643 | biostudies-literature
UnknownAcute modulations in permeability barrier function regulate epidermal cornification: role of caspase-14 and the protease-activated receptor type 2.
Not available
S-EPMC2189608 | biostudies-literature
UnknownEpidermal terminal differentiation depends on B lymphocyte-induced maturation protein-1.
Not available
S-EPMC1986600 | biostudies-literature
UnknownDifferentially expressed late constituents of the epidermal cornified envelope.
Not available
S-EPMC60819 | biostudies-literature
TranscriptomicsMetabolic drivers of human keratinocyte differentiation revealed by integrated metabolome and transcriptome analysis
Epidermal function is maintained through a continuous process called epidermal homeostasis, in which keratinocytes gradually differentiate from proliferating stem cells to dead corneocytes that shed off the skin. We investigated the metabolic rewiring that occur during keratinocyte differentiation. ...
ORGANISM(S): Homo sapiens 
2020-01-01 | GSE136375 | GEO
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