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GenomicsWGBS WT J1 ESC at D3 of EpiLC differentiation
WGBS WT J1 ESC at D3 of EpiLC differentiation
PRJNA885462 | ENA
GenomicsTranscriptomic Analysis of Naïve mESC, Primed mESC and EpiLC
Transcriptomic Analysis of Naïve mESC, Primed mESC and EpiLC
PRJNA803231 | ENA
TranscriptomicsRNA-seq for wild-type and Zbtb2 knock-out clones of mESCs in 2iLIF, EpiLC and SerumLIF conditions.
Zbtb2 mutant mouse embryonic stem cells are defective in exiting the pluripotent state. To determine the transcriptional changes underlying this phenotype we performed RNA-seq of wildtype and Zbtb2 mutant cells; in the naïve pluripotent state in 2iLIF, and after 24h and 48h of exposure to SerumLIF a...
ORGANISM(S): Mus musculus 
2021-07-07 | E-MTAB-9797 | biostudies-arrayexpress
UnknownDissecting signaling hierarchies in the patterning of the mouse primitive streak using micropatterned EpiLC colonies.
Not available
S-EPMC9287665 | biostudies-literature
Methylation profilingWGBS WT J1 ESC at D3 of EpiLC differentiation
We investigate the dynamic of DNA methylation on epiblast differentiation. To this end, we used in vitro Epiblast-like cell (EpiLC) differentiation on WT murine ESCs during 3 days. We next performed bisulfite conversion and whole-genome sequecing to assess methylation levels.
ORGANISM(S): Mus musculus 
2023-10-09 | GSE214463 | GEO
GenomicsmRNA transcriptome analyses of the functions of DDX6-mediated pathways during EpiLC induction
mRNA transcriptome analyses of the functions of DDX6-mediated pathways during EpiLC induction
PRJNA777537 | ENA
TranscriptomicsTranscriptomic Analysis of Naïve mESC, Primed mESC and EpiLC
Pluripotency is a transient feature during early embryonic development, which enables the epiblast cells to generate all the somatic lineages of the organism. Studies using mouse embryo and embryonic stem cell (ESC) indicates that embryonic pluripotency is highly dynamic with a spectrum of pluripote...
ORGANISM(S): Mus musculus 
2022-09-14 | GSE196084 | GEO
GenomicsRNAseq of mll2[Y2602A] mESC and EpiLC
RNAseq of mll2[Y2602A] mESC and EpiLC
PRJEB55369 | ENA
TranscriptomicsGenome-wide transcriptome analysis of Epiblast Like Cells (EpiLC), early Primordial Germ Cells (PGCLCd3) and late Primordial Germ Cells (PGCLCd5) with WT or EsrrbKO background
We report the application of genome-wide RNA-sequencing analysis for WT or EsrrbKO mES cells after transition towards EpiLC and subsequent differentiation in early (d3) or late (d5) PGCLC. We find that formative early and formative late gene signatures were significantly reduced in EsrrbKO EpiLC com...
ORGANISM(S): Mus musculus 
2023-01-25 | GSE184136 | GEO
TranscriptomicsGene expression changes during EpiLC differentiation in embryonic stem cells that are unable to express Tcf15
We analyzed the gene expression changes occuring at the first 24h of EpiLC differentiation in embryonic stem cells in which a regulatory region driving expression of Tcf15 has been deleted. These changes has been compared with wild-type embryonic stem cells.
ORGANISM(S): Mus musculus 
2022-09-30 | GSE132003 | GEO
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