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MetabolomicsSingle-cell lipidomic analysis of the Epithelial-Mesenchymal Transition (EMT) using MALDI-MSI

EMT is a metastasis-promoting process whose heterogeneity has been extensively studied at a gene expression level. EMT also involves reprogramming of lipid metabolism, however there has been little focus on heterogeneity on the lipid level. Here, we use MALDI-MSI to determine the levels of variou...

2026-04-15 | MTBLS12650 | MetaboLights
TranscriptomicsCAMK1D amplification implicated in epithelial-mesenchymal transition in basal-like breast cancer
This SuperSeries is composed of the following subset Series: GSE12811: CAMK1D amplification implicated in epithelial-mesenchymal transition in basal-like breast cancer (expr) GSE12813: CAMK1D amplification implicated in epithelial-mesenchymal transition in basal-like breast cancer (aCGH) Refer to in...
ORGANISM(S): Homo sapiens 
2009-09-08 | E-GEOD-12827 | biostudies-arrayexpress
OtherExtracellular remodelling during oncogenic Ras-induced epithelial-mesenchymal transition facilitates MDCK cell migration.
PeptideAtlas ID: PAe003680. Original data file: O070224-30.mgf. Data published as part of J Proteome Res. 2010 Feb 5;9(2):1007-19 . From the Abstract: {{i}}... To gain insights into extracellular mediators associated with EMT, we conducted an extensive proteomic analysis of the secretome from MDCK ...
ORGANISM(S): Dog, Canine_adenovirus, Canine_calicivirus, Canine_distemper_virus, Canine_minute_virus, Canine_oral_papillomavirus, Canine_papillomavirus_2, Canine_papillomavirus___3, Canine_papillomavirus___4, Canine_parvovirus 
GPM11210000341 | GPMDB
TranscriptomicsGene expression profiling of NSCLC cell lines upon TGFb-induced epithelial-mesenchymal transition (EMT)
Epithelial-mesenchymal transition has been implicated in tumor metastasis, cancer drug resistance and cancer stem cell features. In this study, we examined gene expression profiles of three non-small cell lung cancer cell lines, before and after experimentally induced EMT. We modeled epitheial-mese...
ORGANISM(S): Homo sapiens 
2014-11-19 | E-GEOD-49644 | biostudies-arrayexpress
TranscriptomicsSWI/SNF Chromatin-Remodeling Factor Smarcd3/Baf60c Controls Epithelial-Mesenchymal Transition by Inducing Wnt5a Signaling
We previously identified a gene signature predicted to regulate the epithelial-mesenchymal transition (EMT) in both epithelial tissue stem cells and breast cancer cells. A phenotypic RNA interference (RNAi) screen identified the genes within this 140-gene signature that promoted the conversion of me...
ORGANISM(S): Homo sapiens 
2013-08-19 | E-GEOD-40145 | biostudies-arrayexpress
TranscriptomicsCAMK1D amplification implicated in epithelial-mesenchymal transition in basal-like breast cancer (expr)
Title: CAMK1D amplification implicated in epithelial-mesenchymal transition in basal-like breast cancer Summary: Breast cancer exhibits clinical and molecular heterogeneity, where expression-profiling studies have identified five major molecular subtypes. The basal-like subtype, expressing basal e...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-12811 | biostudies-arrayexpress
GenomicsWhole genome bisulfite sequencing of MDCK cells, before and after TGFB-induced epithelial-mesenchymal transition
Whole genome bisulfite sequencing of MDCK cells, before and after TGFB-induced epithelial-mesenchymal transition Sequencing of bisulfite converted DNA from MDCK cells untreated, and after a 30 days treatment with TGF beta
ORGANISM(S): Canis lupus familiaris 
2014-08-14 | E-GEOD-43697 | biostudies-arrayexpress
GenomicsHistone modification analysis in TGFbeta/TNFalpha treated A549 spheroid cultures
We studied the extent of chromatin remodeling in an in-vitro model of the epithelial-mesenchymal transition (EMT). EMT is induced in spheroid cultures (3D) using simultaneously two cytokines: TGFbeta and TNFalpha. The epithelial-mesenchymal transition (EMT) is a cellular de-differentiation process t...
ORGANISM(S): Homo sapiens 
2013-09-12 | E-GEOD-42374 | biostudies-arrayexpress
TranscriptomicsPrognostic signature of epithelial-mesenchymal transition in breast cancer
Epithelial-mesenchymal transition (EMT), a switch of polarized epithelial cells to a migratory, fibroblastoid phenotype, is considered a key process driving tumor cell invasiveness and metastasis. Using breast cancer cell lines as a model system, we sought to discover gene-expression signatures of ...
ORGANISM(S): Homo sapiens 
2010-04-11 | E-GEOD-13915 | biostudies-arrayexpress
TranscriptomicsCAMK1D amplification implicated in epithelial-mesenchymal transition in basal-like breast cancer (aCGH)
Title: CAMK1D amplification implicated in epithelial-mesenchymal transition in basal-like breast cancer Summary: Breast cancer exhibits clinical and molecular heterogeneity, where expression-profiling studies have identified five major molecular subtypes. The basal-like subtype, expressing basal e...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-12813 | biostudies-arrayexpress
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