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TranscriptomicsGenetic Analysis of Pathways Regulated by the von Hippel-Lindau Tumor Suppressor in Caenorhabditis elegans
The von Hippel-Lindau (VHL) tumor suppressor functions as a ubiquitin ligase that mediates proteolytic inactivation of hydroxylated a subunits of hypoxia-inducible factor (HIF). Although studies of VHL defective renal carcinoma cells suggest the existence of other VHL tumor suppressor pathways, dysr...
ORGANISM(S): Caenorhabditis elegans 
2005-07-20 | E-GEOD-2963 | biostudies-arrayexpress
UnknownEffects Of State Insurance Mandates On Health Care Use And Spending For Autism Spectrum Disorder.
Not available
S-EPMC7011707 | biostudies-literature
UnknownRandomized controlled trial of a video decision support tool for cardiopulmonary resuscitation decision making in advanced cancer.
Not available
S-EPMC4090424 | biostudies-literature
TranscriptomicsGene expression changes in subclones of a Burkitt lymphoma cell line with different patterns of EBV latent infection
In this study we have investigated the gene expression profiles of three different types of subclone all generated by single cell cloning of the same parental EBV positive Burkitt lymphoma cell line Awia-BL. These included EBV negative clones which have lost the virus episome, EBV positive clones w...
ORGANISM(S): Homo sapiens 
2013-01-22 | E-GEOD-42867 | biostudies-arrayexpress
TranscriptomicsA Global View of the Oncogenic Landscape in Nasopharyngeal Carcinoma:An Integrated Analysis at the Genetic and Expression Levels
Previous studies have reported that the tumour cells of nasopharyngeal carcinoma (NPC) exhibit both recurrent chromosome abnormalities and changes in the expression of numerous genes. However, it is not known to what extent changes in the copy number of individual genes are associated with the obser...
ORGANISM(S): Homo sapiens 
2012-12-10 | E-GEOD-34573 | biostudies-arrayexpress
TranscriptomicsGene Expression Analysis Of Plasmablastic Lymphoma Identifies Down Regulation Of B Cell Receptor Signaling and Additional Unique Transcriptional Programs
Plasmablastic lymphoma is a high grade B cell lymphoma with plasmablastic morphology and a terminally differentiated B cell immunophenotype, usually arising in the setting of immunodeficiency and often demonstrating Epstein Barr Virus positivity. The molecular and genetic mechanisms underlying the ...
ORGANISM(S): Homo sapiens 
2015-09-15 | E-GEOD-53117 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of HIF dependent and independent effects of VHL inactivation in C. elegans
The von Hippel-Lindau (VHL) tumor suppressor functions as a ubiquitin ligase that mediates proteolytic inactivation of hydroxylated a subunits of hypoxia-inducible factor (HIF). Although studies of VHL defective renal carcinoma cells suggest the existence of other VHL tumor suppressor pathways, dysr...
ORGANISM(S): Caenorhabditis elegans 
2013-01-30 | E-SMDB-23 | biostudies-arrayexpress
TranscriptomicsRNA Seq in Patients with Primordial Dwarfism
Transcriptome studies in patients with rare genetic diseases can potentially aid in the interpretation of likely causal genetic variation through identification of altered transcript abundance and/or structure. RNA-Seq is the most sensitive assay for both investigating transcript structure and abund...
ORGANISM(S): Homo sapiens 
2013-08-07 | E-ERAD-74 | biostudies-arrayexpress
TranscriptomicsVaccination against yersiniosis induces a specific gill transcriptome biosignature in Atlantic salmon
Simple cost-effective bacterins are the earliest and most successfully used commercial vaccines in fish. In particular, those prepared from Yersinia ruckeri have proven effective at controlling Enteric Red Mouth Disease (ERM) and yersiniosis in rainbow trout and Atlantic salmon, respectively. Howeve...
ORGANISM(S): Salmo salar 
2012-07-21 | E-GEOD-36332 | biostudies-arrayexpress
TranscriptomicsRNA-seq from sorted population of CD8 T cells (50 cells per sample) of human CD8 T memory stem cells (Tscm) subsets defined by surface expression of CD122 or CXCR3
Although it is recognised that CD8+ T memory stem cells (Tscm) are heterogeneous in phenotype and function, very few studies have sought to systematically examine these characteristics, particularly in human samples, as the population as a whole is rare and antigen-specific cells even more so. For e...
ORGANISM(S): Homo sapiens 
2022-03-10 | E-MTAB-10208 | biostudies-arrayexpress
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