Vaccination against yersiniosis induces a specific gill transcriptome biosignature in Atlantic salmon

ABSTRACT: Simple cost-effective bacterins are the earliest and most successfully used commercial vaccines in fish. In particular, those prepared from Yersinia ruckeri have proven effective at controlling Enteric Red Mouth Disease (ERM) and yersiniosis in rainbow trout and Atlantic salmon, respectively. However, the emergence of outbreaks of ERM caused by atypical biotypes of Y. ruckeri and reports of vaccine failure resulting in mass mortality of hatchery Atlantic salmon has reinvigorated interest in vaccines against fish bacterial diseases. Therefore the objective of this study was to identify surrogates of protection against yersiniosis using cDNA microarray to characterise the response of host genes in the gills of unvaccinated and vaccinated Atlantic salmon challenged with Y. ruckeri. Differenti

ORGANISM(S): Salmo salar

SUBMITTER: Andrew Bridle 

PROVIDER: E-GEOD-36332 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress