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GenomicsGenome-Wide Analysis of Host-Chromosome Binding Sites for Epstein-Barr Virus Nuclear Antigen 1 (EBNA1)
The Epstein-Barr Virus (EBV) Nuclear Antigen 1 (EBNA1) protein is required for the establishment of EBV latent infection in proliferating B-lymphocytes. EBNA1 is a multifunctional DNA-binding protein that stimulates DNA replication at the viral origin of plasmid replication (OriP), regulates transc...
ORGANISM(S): Homo sapiens 
2011-07-16 | E-GEOD-30709 | biostudies-arrayexpress
TranscriptomicsExpression Profiles of Monozygotic Twin
The expression level for 15 887 transcripts in lymphoblastoid cell lines from 19 monozygotic twin pairs (10 male, 9 female) were analysed for the effects of genotype and sex. On an average, the effect of twin pairs explained 31% of the variance in normalized gene expression levels, consistent with p...
ORGANISM(S): Homo sapiens 
2008-03-30 | E-GEOD-7624 | biostudies-arrayexpress
TranscriptomicsAnopheles coluzzii RNAseq after para silencing
RNAseq responses in Anopheles coluzzii's 4 days post dsPARA injection (treatment) vs dsGFP injection (control)
ORGANISM(S): Anopheles coluzzii 
2024-04-05 | E-MTAB-12896 | biostudies-arrayexpress
TranscriptomicsCoordination in the transcriptome and proteome of the diatom Thalassiosira pseudonana reveals a diverse phosphorus stress response
Phosphorus (P) is a critical driver of phytoplankton growth and ecosystem structure and function in the ocean. Diatoms are an abundant and widespread functional group of phytoplankton that are responsible for significant amounts of primary production in the ocean, however there has not been a compre...
ORGANISM(S): Thalassiosira pseudonana CCMP1335 
2013-08-03 | E-GEOD-28134 | biostudies-arrayexpress
TranscriptomicsWhole Transcriptome RNA Sequencing Detects Multiple 1a,25-Dihydroxyvitamin D3-Sensitive Metabolic Pathways in Zebrafish Embryos
Vitamin D receptors (VDR) are abundantly expressed in developing zebrafish as early as 48 hours post-fertilization, and prior to the development of a mineralized skeleton, and mature intestine and kidney. We probed the role of VDR in zebrafish biology by examining changes in expression of RNA by wh...
ORGANISM(S): Danio rerio 
2012-06-28 | E-GEOD-38575 | biostudies-arrayexpress
UnknownLymphomas driven by Epstein-Barr virus nuclear antigen-1 (EBNA1) are dependant upon Mdm2.
Not available
S-EPMC6054874 | biostudies-literature
TranscriptomicsThe effect of freeze-thaw cycles on gene expression levels in lymphoblastoid cell lines
Epstein-Barr virus (EBV) transformed lymphoblastoid cell lines (LCLs) are a widely used renewable resource for functional genomic studies in humans. The ability to accumulate multidimensional data pertaining to the same individual cell lines, from complete genomic sequences to detailed gene regulato...
ORGANISM(S): Homo sapiens 
2014-09-05 | E-GEOD-58942 | biostudies-arrayexpress
TranscriptomicsGenome-wide profiling characterizes CRCs with genetic instability and specific routes to HLA class I loss and immunoescape
We compared the expression of genes related to inflammatory cytotoxic functions between MSI and MSS (HLA class I negative and positive) gastrointestinal adenocarcinomas (GIACs), seeking evidence of differences in inflammatory mediators and cytotoxic T-cell responses. Twenty-two GIACs were divided in...
ORGANISM(S): Homo sapiens 
2011-02-28 | E-GEOD-27544 | biostudies-arrayexpress
TranscriptomicsGene expression data from phosphinothricin (PPT) treated Medicago truncatula root nodules
Nitrogen assimilation in plants is a tightly regulated process that integrates developmental and environmental signals. The legume-rhizobial symbiosis results in the formation of a specialized organ called root nodule, where the rhizobia fixes atmospheric nitrogen into ammonia. Ammonia is assimilate...
ORGANISM(S): Medicago truncatula 
2012-05-08 | E-GEOD-34155 | biostudies-arrayexpress
TranscriptomicsTranscription factor Runx1 cooperates with MyoD and c-Jun to regulate the balance of myoblast proliferation/differentiation [Expression Study]
Runx1 is expressed in regenrating muscle, specifically in the muscle adult stem cells- the satellite cells. Its exact role and target genes were yet to be identified This experiment aimed at determining the Runx1 regulated genes in muscle regeneration, specifically in Satellite cells To elucidate th...
ORGANISM(S): Mus musculus 
2015-07-23 | E-GEOD-55556 | biostudies-arrayexpress
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