Epstein Seth S - OmicsDI

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mRNA Expression Comparison Between Igfbp7-null and wild type mice at Lactation Day 3

Insulin like growth factor binding protein 7, Igfbp7, is a secreted protein that in addition to modulating insulin and insulin-like growth factor signaling, it acts as a tumor suppressor gene in breast and other cancers. To elucidate the role of Igfbp7 in regulating the proliferation and differentia...

ORGANISM(S): Mus musculus

2014-09-02 | E-GEOD-45118 | biostudies-arrayexpress

The orphan nuclear hormone receptor ERR-beta controls rod photoreceptor survival.

Mutation of rod photoreceptor-enriched transcription factors is a major cause of inherited blindness. We identified the orphan nuclear hormone receptor ERRÎ² as selectively expressed in rod photoreceptors. Overexpression of ERRÎ² induces expression of rod-specific genes in retinas of both wildtype ...

ORGANISM(S): Mus musculus

2010-07-30 | E-GEOD-21944 | biostudies-arrayexpress

Expression profile of sweat gland label retaining cells (LRCs)

We have used the slow cycling property, found in hair follicle stem cells, to look for LRCs in sweat glands as putative stem cells. Gene expression profiling allowed us to determine the common and unique genes expressed in SG LRCs and non-LRCs. This allowed us to probe for the signaling pathways act...

ORGANISM(S): Mus musculus

2013-12-24 | E-GEOD-49011 | biostudies-arrayexpress

Comprehensive molecular characterization of gastric adenocarcinoma.

Not available

S-EPMC4170219 | biostudies-literature

CSR-1 mediates RNA activation, RNAa, a self-RNA recognition pathway that promotes gene expression in the C. elegans germline

Epigenetic inheritance is the transmission of information independently of the nucleotide sequence of the genome. A fundamental question in biology is to what extent does epigenetics contribute to trans-generational inheritance. Here we investigate the role of Argonaute-small-RNA pathways in epigen...

ORGANISM(S): Caenorhabditis elegans

2013-12-23 | E-GEOD-49532 | biostudies-arrayexpress

MEDULLOBLASTOMA

Not available

S-EPMC4046290 | biostudies-literature

Adjuvant nab-Paclitaxel + Gemcitabine in Resected Pancreatic Ductal Adenocarcinoma: Results From a Randomized, Open-Label, Phase III Trial.

Not available

S-EPMC10082313 | biostudies-literature

Challenges of one-year longitudinal follow-up of a prospective, observational cohort study using an anonymised database: recommendations for trainee research collaboratives.

Not available

S-EPMC6909648 | biostudies-literature

Impact of postoperative acute kidney injury in patients undergoing major gastrointestinal surgery on 1-year survival and renal outcomes: a national multicentre cohort study.