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ProteomicsComparing different pregnant mare serum gonadotropin products: surprising differences in protein content and a new sialic acid O-acetylation
Equine chorionic gonadotropin (eCG) is a widely used hormone to synchronize the female cycle and induce estrusestruses in livestock breeding. eCG is a heterodimeric glycoprotein composed of non-covalently linked α- and β-chains whose glycosylation profiles determine the in vivo activity of the hormo...
ORGANISM(S): Equus caballus (Horse) 
2025-05-06 | PXD042535 | Pride
O-acetylation Equine chorionic gonadotropin (ecg) and lutropin Pregnant mare serum gonadotropin (pmsg) Sulfation 
TranscriptomicsCCAAT/Enhancer Binding Proteins (C/EBP)-M-NM-1 and -M-NM-2 are Essential for Ovulation, Luteinization and the Expression of Key Target Genes
Luteinizing hormone (LH) activation of the EGF receptor/RAS/ERK1/2 pathway is essential for ovulation and luteinization because granulosa cell depletion of Erk1/2 (Erk1/2gc-/- mice) renders mice completely infertile. Because of their potential as mediators of ERK1/2-dependent granulosa cell differe...
ORGANISM(S): Mus musculus 
2010-12-31 | E-GEOD-23084 | biostudies-arrayexpress
TranscriptomicsERK1/2 in Ovarian Granulosa Cells are Essential for Female Fertility
A surge of luteinizing hormone (LH) from the pituitary gland triggers ovulation, oocyte maturation, and luteinization for successful reproduction in mammals. Since the signaling molecules RAS and ERK1/2 are activated by a LH surge in granulosa cells of preovulatory follicles, we disrupted Erk1/2 in ...
ORGANISM(S): Mus musculus 
2009-03-20 | E-GEOD-15315 | biostudies-arrayexpress
TranscriptomicsExpression data from mouse cumulus cells
Follicle stimulating hormone (FSH) and epidermal growth factor (EGF) are currently used on cumulus-oocyte complexes to mimic the luteinizing hormone surge in vitro and induce oocyte maturation and cumulus expansion. We have previously shown that addition of exogenous recombinant growth differentiati...
ORGANISM(S): Mus musculus 
2011-12-10 | E-GEOD-19327 | biostudies-arrayexpress
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