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UnknownAcute ACAT1/SOAT1 Blockade Increases MAM Cholesterol and Strengthens ER-Mitochondria Connectivity.
Not available
S-EPMC10059652 | biostudies-literature
UnknownGRP75-faciliated Mitochondria-associated ER Membrane (MAM) Integrity controls Cisplatin-resistance in Ovarian Cancer Patients.
Not available
S-EPMC9066115 | biostudies-literature
UnknownTOM20-mediated transfer of Bcl2 from ER to MAM and mitochondria upon induction of apoptosis.
Not available
S-EPMC7884705 | biostudies-literature
UnknownProteomic analysis of mitochondrial-associated ER membranes (MAM) during RNA virus infection reveals dynamic changes in protein and organelle trafficking.
Not available
S-EPMC4348417 | biostudies-literature
UnknownComparative Proteomic Analysis of the Mitochondria-associated ER Membrane (MAM) in a Long-term Type 2 Diabetic Rodent Model.
Not available
S-EPMC5437025 | biostudies-literature
UnknownPolyGA targets the ER stress-adaptive response by impairing GRP75 function at the MAM in C9ORF72-ALS/FTD.
Not available
S-EPMC9547809 | biostudies-literature
ProteomicsUrolithin A protects hepatocytes from palmitic acid-induced ER stress by regulating calcium homeostasis in the MAM
An ellagitannin-derived metabolite Urolithin A (UA) has emerged as a potential therapeutic agent for metabolic disorders due to its antioxidant, anti-inflammatory, and mitochondrial function-improving properties, but its efficacy in protecting against ER stress remains underexplored. The endoplasmic...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-10-02 | MSV000096011 | MassIVE
ProteomicsRevisiting the relevance of the accumulation of apolipoprotein E (APOE) in mitochondria-associated ER membranes: Investi-gation of hepatic protein-protein interactions of APOE with LONP1, TOMM40 and VDAC1
Investigating the subcellular distribution and protein interaction of APOE and the modulation by cellular stress signals, we aimed to contribute to the elucidation of putative novel functions. We identified APOE as hepatic mitochondria-associated ER-membranes (MAM) protein, where it most likely inte...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055281 | Pride
Mitochondria-er contacts (merc) Mam Stress response Proteome analysis Subcellular distribution Liver Apoe4 
ProteomicsContact-ID, a new tool for profiling organelle-membrane contact sites, reveals regulatory proteins of mitochondrial-associated membrane formation
The mitochondria-associated membrane (MAM) has emerged as a cellular signaling hub regulating various cellular processes. However, its molecular components remain unclear owing to lack of reliable methods to purify the intact MAM proteome in a physiological context. Here, we introduce Contact-ID, a ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000084362 | MassIVE
ProteomicsProteomic Analysis of Retinal Mitochondria-associated ER Membranes Identified Novel Proteins of Retinal Degeneration in Long-term Diabetes
The mitochondria-associated endoplasmic reticulum (ER) membrane (MAM) is the physical contact site between the ER and the mitochondria and plays a vital role in the regulation of calcium trafficking and bioenergetics. Previous studies suggest that disturbances in calcium trafficking and dysregulatio...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-10-15 | PXD033040 | Pride
Diabetic retinopathy  type 1 diabetes  mitochondria-associated er membrane  proteomic  retinal degeneration 
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