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ProteomicsMS-based quantitative proteomic analysis of MAM from WT and obese mice.
Diabetic cardiomyopathy (DCM) strongly leads to heart failure, notably with preserved ejection fraction (HFpEF). The involvement of mitochondria-associated reticular membranes (MAM) in T2D-related metabolic disorders starts to be demonstrated. In order to characterize the cardiac phenotype of an obe...
ORGANISM(S): Mus musculus (Mouse) 
2025-06-16 | PXD054672 | Pride
Mitochondria-associated reticular membranes (mam) Mouse Obesity Diabetic cardiomyopathy Nanolc-ms/ms 
TranscriptomicsComparison of metastasis-inclined microenvironment (MIM) and metastasis-averse microenvironment (MAM) HCC patients
To determine the role of the hepatic microenvironment in HCC metastasis, we compared the gene expression profiles of 20 noncancerous surrounding hepatic tissues from two HCC patient groups, those with primary HCC together with venous metastasis which we termed a metastasis-inclined microenvironment ...
ORGANISM(S): Homo sapiens 
2010-07-01 | E-GEOD-5093 | biostudies-arrayexpress
ProteomicsMicrobial anti-inflammatory Molecule is a key protein processed and exported to Faecalibacterium duncaniae envelope
MAM (Microbial-Anti-Inflammatory Molecule) is a 14,5 kDa protein that is one of the best-known effector molecules with anti-inflammatory properties in Faecalibacterium duncaniae, a critical species in the human gut microbiota. Despite its importance, MAM function and molecular features remain poorly...
ORGANISM(S): Faecalibacterium prausnitzii A2-165 
2025-06-30 | PXD057939 | Pride
Proteomic and peptidomic 
GenomicsEnterobacter roggenkampii strain:MAM-MRK.Er.2025
Enterobacter roggenkampii strain:MAM-MRK.Er.2025 Genome sequencing
PRJNA1337114 | ENA
GenomicsAcinetobacter variabilis strain:MAM-SAU.Av.2025
Acinetobacter variabilis strain:MAM-SAU.Av.2025 Genome sequencing
PRJNA1336764 | ENA
ProteomicsAltered mitochondria-associated ER membranes (MAM) function shifts mitochondrial metabolism in amyotrophic lateral sclerosis (ALS)- BioID Data
Mitochondrial function is modulated by its functional interaction with the endoplasmic reticulum. Recent research indicates that these contacts are disrupted in familial models of amyotrophic lateral sclerosis. We report here this impairment in the crosstalk between mitochondria and the endoplasmic ...
ORGANISM(S): Mus musculus (Mouse) 
2024-07-19 | PXD053415 | Pride
Mam Sod Als Cholesterol Bioid 
ProteomicsAltered mitochondria-associated ER membranes (MAM) function shifts mitochondrial metabolism in amyotrophic lateral sclerosis (ALS)
Mitochondrial function is modulated by its functional interaction with the endoplasmic reticulum. Recent research indicates that these contacts are disrupted in familial models of amyotrophic lateral sclerosis. We report here this impairment in the crosstalk between mitochondria and the endoplasmic ...
ORGANISM(S): Mus musculus (Mouse) 
2024-07-19 | PXD053253 | Pride
Mitochondria Als Amyotrophic lateral sclerosis Mam Mouse 
TranscriptomicsCycad Genotoxin Methylazoxymethanol (MAM) Modulates Cellular Pathways Involved in Cancer and Neurodegenerative Disease
Methylazoxymethanol (MAM), the genotoxic metabolite of the cycad azoxyglucoside cycasin, induces genetic alterations in bacteria, yeast, plants, insects and mammalian cells, but adult nerve cells are thought to be unaffected. We show that the brains of young adult mice treated with a single systemic...
ORGANISM(S): Mus musculus 
2013-01-10 | E-GEOD-26600 | biostudies-arrayexpress
TranscriptomicsAbnormalities in Behaviour, Histology and Prefrontal Cortical Gene Expression Profiles Relevant to Schizophrenia in Embryonic Day 17 MAM-Exposed C57BL/6 Mice
Gestational and perinatal disruption of neural development increases the risk of developing schizophrenia (SCZ) later in life. Embryonic day 17 (E17) methylazoxymethanol (MAM) treatment leads to histological, physiological and behavioural abnormalities in post-puberty rats resembling those described...
ORGANISM(S): Mus musculus 
2019-01-09 | GSE108925 | GEO
TranscriptomicsCycad Genotoxin Methylazoxymethanol (MAM) Modulates Cellular Pathways Involved in Cancer and Neurodegenerative Disease
Methylazoxymethanol (MAM), the genotoxic metabolite of the cycad azoxyglucoside cycasin, induces genetic alterations in bacteria, yeast, plants, insects and mammalian cells, but adult nerve cells are thought to be unaffected. We show that the brains of young adult mice treated with a single systemic...
ORGANISM(S): Mus musculus 
2013-01-10 | GSE26600 | GEO
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